Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XPO1 | O14980 | 10/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 7/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1592486 | 0.79 | XPO1 (0.48) | XPO1NTRK1 | |
| SCHEMBL30346302 | 0.78 | XPO1 (0.63) | XPO1NTRK1TRPV1 | |
| SCHEMBL1592487 | 0.78 | XPO1 (0.43) | XPO1NTRK1TRPV1 | |
| SCHEMBL1593000 | 0.69 | XPO1 (0.48) | XPO1TRPV1 | |
| SCHEMBL1593002 | 0.68 | XPO1 (0.44) | XPO1TRPV1 | |
| SCHEMBL1592522 | 0.67 | XPO1 (0.47) | XPO1 | |
| SCHEMBL24465012 | 0.67 | XPO1 (0.40) | XPO1NTRK1 | |
| SCHEMBL1592800 | 0.67 | XPO1 (0.48) | XPO1 | |
| SCHEMBL20880320 | 0.64 | XPO1 (0.46) | XPO1 | |
| SCHEMBL8406375 | 0.63 | XPO1 (0.60) | XPO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2152692-A2 | COMPOUNDS WITH ANTI-CANCER ACTIVITY | Canbas Co. Ltd. (JP) | 2010-02-17 | — | — | EP | claimed |
| WO-2009031040-A2 | COMPOUNDS WITH ANTI-CANCER ACTIVITY | CANBAS CO., LTD. (JP) | 2009-03-12 | — | — | WO | claimed |