Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 17/20 | 0.51 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL496121 | 0.86 | HTR4 (0.48) | HTR4HCRTR1 | |
| SCHEMBL2441649 | 0.86 | HTR4 (0.48) | HTR4HCRTR1 | |
| SCHEMBL496159 | 0.77 | HTR4 (0.50) | HTR4CNR1CNR2 | |
| SCHEMBL2927633 | 0.77 | HTR4 (0.47) | HTR4 | |
| SCHEMBL2927632 | 0.77 | HTR4 (0.47) | HTR4 | |
| SCHEMBL2477357 | 0.77 | HCRTR1 (0.64) | HCRTR1 | |
| SCHEMBL496546 | 0.77 | HCRTR1 (0.64) | HCRTR1 | |
| SCHEMBL13538941 | 0.76 | HTR4 (0.45) | HTR4HCRTR1 | |
| SCHEMBL27873054 | 0.75 | HTR4 (0.50) | HTR4CNR1CNR2 | |
| SCHEMBL27791769 | 0.75 | HTR4 (0.50) | HTR4CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2164847-A1 | 3-AZA-BICYCLO[3.3.0]OCTANE COMPOUNDS | Actelion Pharmaceuticals Ltd. (CH) | 2010-03-24 | — | — | EP | disclosed |
| WO-2009004584-A1 | 3-AZA-BICYCLO[3.3.0]OCTANE COMPOUNDS | ACTELION PHARMACEUTICALS LTD (CH) | 2009-01-08 | — | — | WO | disclosed |