Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL496121 | 1.00 | HTR4 (0.48) | HTR4HCRTR1 | |
| SCHEMBL2927632 | 0.92 | HTR4 (0.47) | HTR4 | |
| SCHEMBL2927633 | 0.92 | HTR4 (0.47) | HTR4 | |
| SCHEMBL496719 | 0.89 | HTR4 (0.44) | HTR4 | |
| SCHEMBL3637580 | 0.86 | HTR4 (0.51) | HTR4HCRTR1 | |
| SCHEMBL982052 | 0.80 | HTR4 (0.48) | HTR4 | |
| SCHEMBL1340259 | 0.80 | MTNR1B (0.39) | HTR4HCRTR1 | |
| SCHEMBL5214369 | 0.79 | HTR4 (0.64) | HTR4 | |
| SCHEMBL1571823 | 0.76 | HTR4 (0.47) | HTR4 | |
| SCHEMBL3677156 | 0.76 | HCRTR1 (0.40) | HTR4HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2164847-B1 | 3-AZA-BICYCLO[3.3.0]OCTANE COMPOUNDS | ACTELION PHARMACEUTICALS LTD (CH) | 2011-09-14 | — | — | EP | disclosed |