Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 8/20 | 0.73 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.73 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.73 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.66 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.66 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.66 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | DRD2 | P14416 | 2/20 | 0.60 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.58 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.58 |
| ▸ | HTR2C | P28335 | 1/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.58 |
| ▸ | DRD4 | P21917 | 1/20 | 0.57 |
| ▸ | AKT1 | P31749 | 1/20 | 0.56 |
| ▸ | AKT2 | P31751 | 1/20 | 0.56 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8863557 | 0.88 | OPRM1 (0.91) | OPRM1OPRK1OPRL1CHRM1CHRM2 | |
| SCHEMBL11223608 | 0.88 | OPRM1 (0.86) | OPRM1OPRK1OPRL1CHRM1DRD4 | |
| SCHEMBL3665096 | 0.85 | OPRM1 (1.00) | OPRM1OPRK1OPRL1CHRM1DRD2 | |
| Oxalic Acid SCHEMBL5778025 | 0.83 | OPRM1 (0.91) | OPRM1OPRK1OPRL1ALDH1A1DRD2 | |
| SCHEMBL3630723 | 0.82 | OPRM1 (0.66) | OPRM1OPRK1OPRL1CHRM1CHRM2 | |
| SCHEMBL3895786 | 0.81 | CHRM1 (0.92) | OPRM1OPRK1OPRL1CHRM1CHRM2 | |
| SCHEMBL6487094 | 0.81 | OPRM1 (0.61) | OPRM1OPRK1OPRL1CHRM1CHRM2 | |
| SCHEMBL4919819 | 0.80 | CHRM1 (1.00) | OPRM1OPRK1OPRL1CHRM1CHRM2 | |
| SCHEMBL4572894 | 0.80 | CHRM1 (1.00) | OPRM1OPRK1OPRL1CHRM1CHRM2 | |
| SCHEMBL27056694 | 0.80 | CHRM1 (1.00) | OPRM1OPRK1OPRL1CHRM1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155676-A2 | COMPOUNDS WITH ANTIPARASITIC ACTIVITY, APPLICATIONS THEREOF TO THE TREATMENT OF INFECTIOUS DISEASES CAUSED BY APICOMPLEXANS | Commissariat à l'Energie Atomique (FR) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008146172-A2 | COMPOUNDS WITH ANTIPARASITIC ACTIVITY, APPLICATIONS THEREOF TO THE TREATMENT OF INFECTIOUS DISEASES CAUSED BY APICOMPLEXANS | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2008-12-04 | — | — | WO | disclosed |