SCHEMBL3637683

SCHEMBL3637683

C=CCSCCNC(=O)CCn1cccc1

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.46
HSD17B10 Q99714 1/20 0.46
HPGD P15428 5/20 0.44
MEN1 O00255 6/20 0.42
KMT2A Q03164 6/20 0.42
GAA P10253 1/20 0.39
POLB P06746 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
HTT P42858 1/20 0.35
ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13043764 0.75
SCHEMBL12086550 0.72 TSHR (0.44) TSHRHSD17B10HPGDMEN1KMT2A
SCHEMBL3631111 0.72 TSHR (0.55) TSHRHSD17B10HPGDMEN1KMT2A
SCHEMBL16610100 0.70 TSHR (0.53) TSHRHSD17B10HPGDMEN1KMT2A
SCHEMBL13712850 0.69 TSHR (0.52) TSHRHSD17B10HPGDMEN1KMT2A
SCHEMBL11883175 0.68 MAPT (0.41) TSHRHSD17B10HPGDKMT2AGAA
SCHEMBL11616630 0.68 TSHR (0.39) TSHRALDH1A1
SCHEMBL11844355 0.67 HPGD (0.48) HPGD
SCHEMBL13712852 0.67 TSHR (0.50) TSHRHSD17B10HPGDMEN1KMT2A
SCHEMBL11492453 0.65 CASP2 (0.48) TSHRHSD17B10HPGDMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8343212-B2 Polymer coatings on medical devices Biotectix, LLC (US) 2013-01-01 US disclosed
US-8343212-B2 Polymer coatings on medical devices Biotectix, LLC (US) 2013-01-01 US disclosed
EP-2155275-B1 POLYMER COATINGS ON MEDICAL DEVICES BIOTECTIX LLC (US) 2012-09-05 EP disclosed
EP-2155275-B1 POLYMER COATINGS ON MEDICAL DEVICES BIOTECTIX LLC (US) 2012-09-05 EP disclosed
US-20100312331-A1 POLYMER COATINGS ON MEDICAL DEVICES CHAMELEON BIOSURFACES LIMITED (GB) 2010-12-09 US disclosed
US-20100312331-A1 POLYMER COATINGS ON MEDICAL DEVICES CHAMELEON BIOSURFACES LIMITED (GB) 2010-12-09 US disclosed
EP-2155275-A2 POLYMER COATINGS ON MEDICAL DEVICES Chameleon Biosurfaces Limited (GB) 2010-02-24 EP disclosed
WO-2008139200-A2 POLYMER COATINGS ON MEDICAL DEVICES CHAMELEON BIOSURFACES LIMITED (GB) 2008-11-20 WO disclosed
WO-2008139200-A2 POLYMER COATINGS ON MEDICAL DEVICES CHAMELEON BIOSURFACES LIMITED (GB) 2008-11-20 WO disclosed