Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 7/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 7/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 7/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16610100 | 0.80 | TSHR (0.53) | TSHRHSD17B10HPGDMEN1KMT2A | |
| SCHEMBL13712850 | 0.79 | TSHR (0.52) | TSHRHSD17B10HPGDMEN1KMT2A | |
| SCHEMBL13712852 | 0.76 | TSHR (0.50) | TSHRHSD17B10HPGDMEN1KMT2A | |
| SCHEMBL1241798 | 0.75 | HDAC3 (0.59) | TSHRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL11492453 | 0.74 | CASP2 (0.48) | TSHRHSD17B10HPGDMEN1KMT2A | |
| SCHEMBL928881 | 0.73 | — | — | |
| SCHEMBL4411249 | 0.72 | TSHR (0.51) | TSHRHSD17B10HPGDMEN1KMT2A | |
| SCHEMBL3637683 | 0.72 | TSHR (0.46) | TSHRHSD17B10HPGDMEN1KMT2A | |
| SCHEMBL17953253 | 0.71 | HDAC3 (0.45) | HPGDHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL636785 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8343212-B2 | Polymer coatings on medical devices | Biotectix, LLC (US) | 2013-01-01 | — | — | US | disclosed |
| EP-2155275-B1 | POLYMER COATINGS ON MEDICAL DEVICES | BIOTECTIX LLC (US) | 2012-09-05 | — | — | EP | disclosed |
| US-20100312331-A1 | POLYMER COATINGS ON MEDICAL DEVICES | CHAMELEON BIOSURFACES LIMITED (GB) | 2010-12-09 | — | — | US | disclosed |
| EP-2155275-A2 | POLYMER COATINGS ON MEDICAL DEVICES | Chameleon Biosurfaces Limited (GB) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008139200-A2 | POLYMER COATINGS ON MEDICAL DEVICES | CHAMELEON BIOSURFACES LIMITED (GB) | 2008-11-20 | — | — | WO | disclosed |