Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9004553 | 0.79 | STAT3 (0.32) | STAT3 | |
| SCHEMBL8107739 | 0.78 | — | — | |
| SCHEMBL13039627 | 0.77 | ALDH1A1 (0.39) | STAT3 | |
| SCHEMBL21166402 | 0.74 | — | — | |
| SCHEMBL1662210 | 0.73 | OXER1 (0.30) | — | |
| SCHEMBL20809361 | 0.72 | — | — | |
| SCHEMBL6647762 | 0.72 | — | — | |
| SCHEMBL24384622 | 0.71 | ALDH1A1 (0.40) | — | |
| SCHEMBL12849491 | 0.70 | ALDH1A1 (0.56) | STAT3 | |
| SCHEMBL4391467 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8410135-B2 | 4,5 dihydro-(1H)-pyrazole derivatives as cannabinoid CB1 receptor modulators | SOLVAY PHARMACEUTICALS B.V. (NL) | 2013-04-02 | — | — | US | disclosed |
| US-8410135-B2 | 4,5 dihydro-(1H)-pyrazole derivatives as cannabinoid CB1 receptor modulators | SOLVAY PHARMACEUTICALS B.V. (NL) | 2013-04-02 | — | — | US | disclosed |
| US-8410135-B2 | 4,5 dihydro-(1H)-pyrazole derivatives as cannabinoid CB1 receptor modulators | SOLVAY PHARMACEUTICALS B.V. (NL) | 2013-04-02 | — | — | US | disclosed |
| EP-2158184-A2 | 4,5-DIHYDRO-(1H)-PYRAZOLE DERIVATIVES AS CANNABINOID CB1 RECEPTOR MODULATORS | Solvay Pharmaceuticals B.V. (NL) | 2010-03-03 | — | — | EP | disclosed |
| WO-2008152086-A2 | 4,5-DIHYDRO-(1H)-PYRAZOLE DERIVATIVES AS CANNABINOID CB1 RECEPTOR MODULATORS | SOLVAY PHARMACEUTICALS B.V. (NL) | 2008-12-18 | — | — | WO | disclosed |
| WO-2008152086-A2 | 4,5-DIHYDRO-(1H)-PYRAZOLE DERIVATIVES AS CANNABINOID CB1 RECEPTOR MODULATORS | SOLVAY PHARMACEUTICALS B.V. (NL) | 2008-12-18 | — | — | WO | disclosed |
| US-20080312276-A1 | 4,5 Dihydro-(1H)-Pyrazole Derivatives as Cannabinoid CB1 Receptor Modulators | SOLVAY PHARMACEUTICALS, B.V. | 2008-12-18 | — | — | US | disclosed |
| US-20080312276-A1 | 4,5 Dihydro-(1H)-Pyrazole Derivatives as Cannabinoid CB1 Receptor Modulators | SOLVAY PHARMACEUTICALS, B.V. | 2008-12-18 | — | — | US | disclosed |
| US-20080312276-A1 | 4,5 Dihydro-(1H)-Pyrazole Derivatives as Cannabinoid CB1 Receptor Modulators | SOLVAY PHARMACEUTICALS, B.V. | 2008-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312276-A1 | 4,5 Dihydro-(1H)-Pyrazole Derivatives as Cannabinoid CB1 Receptor Modulators | CNR1, CNR2, GPR35 | STAT3 3325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.