Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 6/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | IGFBP5 | P24593 | 2/20 | 0.38 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2907089 | 0.94 | GRM2 (0.46) | GRM2ALDH1A1LCKKMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL3330671 | 0.93 | GRM2 (0.45) | GRM2ALDH1A1LCKKMT2AKDM4E | |
| SCHEMBL2905327 | 0.90 | GRM2 (0.49) | GRM2ALOX15ALDH1A1DHODHKMT2A | |
| SCHEMBL3638275 | 0.86 | GRM2 (0.40) | GRM2ALOX15ALDH1A1LCKKMT2A | |
| SCHEMBL2908172 | 0.83 | CSNK2A1 (0.46) | ALDH1A1LCKKMT2AKDM4ETDP1 | |
| SCHEMBL2908924 | 0.81 | KDM4E (0.49) | ALOX15ALDH1A1LCKKDM4EMAPT | |
| SCHEMBL3332188 | 0.81 | ALDH1A1 (0.50) | GRM2ALDH1A1KMT2AKDM4EMAPT | |
| SCHEMBL561686 | 0.80 | KDM4E (0.54) | ALOX15ALDH1A1LCKKMT2AKDM4E | |
| SCHEMBL31389316 | 0.80 | KDM4E (0.54) | ALOX15ALDH1A1LCKKMT2AKDM4E | |
| SCHEMBL28052017 | 0.79 | ALDH1A1 (0.48) | ALOX15ALDH1A1DHODHKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2148871-A1 | QUINOLINE-CARBOXAMIDE DERIVATIVES AS P2Y12 ANTAGONISTS | Sanofi-Aventis (FR) | 2010-02-03 | — | — | EP | disclosed |
| WO-2008128647-A1 | QUINOLINE-CARBOXAMIDE DERIVATIVES AS P2Y12 ANTAGONISTS | SANOFI-AVENTIS (FR) | 2008-10-30 | — | — | WO | disclosed |