Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TNKS | O95271 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | GABRP | O00591 | 1/20 | 0.45 |
| ▸ | GABRD | O14764 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL561686 | 1.00 | KDM4E (0.54) | KDM4EALOX15MEN1KMT2AALDH1A1 | |
| SCHEMBL2467305 | 0.84 | ALDH1A1 (0.65) | KDM4EALOX15MEN1KMT2AALDH1A1 | |
| SCHEMBL72379 | 0.84 | KDM4E (0.70) | KDM4EALOX15MEN1KMT2AALDH1A1 | |
| SCHEMBL30002312 | 0.83 | SMN1; SMN2 (0.54) | KDM4EALOX15MEN1KMT2AALDH1A1 | |
| SCHEMBL1733527 | 0.83 | SMN1; SMN2 (0.54) | KDM4EALOX15MEN1KMT2AALDH1A1 | |
| SCHEMBL2935296 | 0.83 | GABRP (0.48) | KDM4EALOX15MEN1KMT2AMAPT | |
| SCHEMBL2908924 | 0.83 | KDM4E (0.49) | KDM4EALOX15ALDH1A1MAPTHPGD | |
| SCHEMBL2072605 | 0.83 | ALOX15 (0.77) | KDM4EALOX15MEN1KMT2AALDH1A1 | |
| SCHEMBL1315731 | 0.83 | KDM4E (0.52) | KDM4EALOX15MEN1KMT2AALDH1A1 | |
| SCHEMBL31389251 | 0.83 | ALOX15 (0.77) | KDM4EALOX15MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119264047-A | Quinoline derivative histone deacetylase inhibitor and preparation method and application thereof | 山东大学 | 2025-01-07 | — | — | CN | disclosed |