SCHEMBL3638466

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4443078	1.00	TNFRSF1A (0.46)	TNFRSF1AALDH1A1RXFP1LMNAKDM4E
	SCHEMBL4446583	0.87	TNFRSF1A (0.46)	TNFRSF1AALDH1A1RXFP1LMNAKDM4E
	SCHEMBL4446586	0.87	TNFRSF1A (0.46)	TNFRSF1AALDH1A1RXFP1LMNAKDM4E
	SCHEMBL14025189	0.87	RXFP1 (0.41)	ALDH1A1RXFP1LMNAMEN1KMT2A
	SCHEMBL4443072	0.87	ALDH1A1 (0.47)	ALDH1A1RXFP1LMNAMAPTMEN1
	SCHEMBL4443068	0.87	ALDH1A1 (0.47)	ALDH1A1RXFP1LMNAMAPTMEN1
	SCHEMBL4456780	0.86	MEN1 (0.47)	TNFRSF1AALDH1A1RXFP1LMNAMEN1
	SCHEMBL4456783	0.86	MEN1 (0.47)	TNFRSF1AALDH1A1RXFP1LMNAMEN1
	SCHEMBL4447518	0.86	TNFRSF1A (0.47)	TNFRSF1AALDH1A1RXFP1LMNAKDM4E
	SCHEMBL4450275	0.86	TNFRSF1A (0.47)	TNFRSF1AALDH1A1RXFP1LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.