Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGK1 | O00141 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 8/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3638579 | 0.83 | ALDH1A1 (0.54) | MAPTALDH1A1SMN1; SMN2RAB9AMEN1 | |
| SCHEMBL48824 | 0.72 | ALDH1A1 (0.46) | ALDH1A1RAB9AMEN1LMNAL3MBTL1 | |
| SCHEMBL31312635 | 0.70 | RAB9A (0.47) | MAPTALDH1A1SMN1; SMN2RAB9AMEN1 | |
| SCHEMBL3638578 | 0.69 | RAB9A (0.41) | MAPTALDH1A1SMN1; SMN2RAB9AMEN1 | |
| SCHEMBL2396550 | 0.67 | MAPT (0.63) | MAPTALDH1A1SMN1; SMN2RAB9AMEN1 | |
| SCHEMBL3602972 | 0.65 | PIK3CD (0.50) | MAPTALDH1A1SMN1; SMN2RAB9ATHRB | |
| SCHEMBL20526726 | 0.65 | MEN1 (0.39) | MAPTALDH1A1SMN1; SMN2RAB9AMEN1 | |
| SCHEMBL20526728 | 0.65 | MEN1 (0.39) | MAPTALDH1A1SMN1; SMN2RAB9AMEN1 | |
| SCHEMBL48371 | 0.64 | PIK3CD (0.67) | MAPTSMN1; SMN2RAB9ATHRBMEN1 | |
| SCHEMBL31312581 | 0.63 | KDM4E (0.39) | MAPTALDH1A1SMN1; SMN2RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100093690-A1 | 5-PHENYLTHIAZOLE DERIVATIVES AND USE AS PI3 KINASE INHIBITORS | BRUCE IAN | 2010-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100093690-A1 | 5-PHENYLTHIAZOLE DERIVATIVES AND USE AS PI3 KINASE INHIBITORS | PIK3CA, PIK3R5, PIP5K1B | SGK1 398/4885MAPT 1132/4885ALDH1A1 3271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.