Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 1/20 | 0.30 |
| ▸ | GABRD | O14764 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.30 |
| ▸ | GABRE | P78334 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15284409 | 0.81 | HCAR2 (0.42) | KCNH2NOS2HRH3HCAR3HCAR2 | |
| SCHEMBL27797675 | 0.79 | IKBKB (0.41) | KCNH2NOS2HRH3HCAR3HCAR2 | |
| SCHEMBL9322943 | 0.76 | HCAR2 (0.44) | KCNH2HCAR3HCAR2 | |
| SCHEMBL7579081 | 0.73 | KCNH2 (0.43) | KCNH2HCAR3HCAR2IKBKB | |
| Acetic Acid SCHEMBL27781427 | 0.72 | HCAR2 (0.38) | KCNH2NOS2HRH3HCAR3HCAR2 | |
| Acetic Acid SCHEMBL27806863 | 0.72 | PARP1 (0.39) | KCNH2NOS2HRH3HCAR3HCAR2 | |
| SCHEMBL3840247 | 0.72 | HRH3 (0.42) | KCNH2NOS2HRH3ESR1ESR2 | |
| SCHEMBL1532157 | 0.72 | NOS2 (0.43) | KCNH2NOS2HRH3HCAR3HCAR2 | |
| SCHEMBL6003432 | 0.71 | HRH3 (0.39) | KCNH2NOS2HRH3HCAR3HCAR2 | |
| SCHEMBL5924367 | 0.71 | NOS2 (0.46) | KCNH2NOS2HRH3ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2170913-A1 | PLATINUM (IV) COMPLEXES | Platco Technologies (Proprietary) Limited (ZA) | 2010-04-07 | — | — | EP | disclosed |
| WO-2008155727-A1 | PLATINUM (IV) COMPLEXES | PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) | 2008-12-24 | — | — | WO | disclosed |