Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RARA | P10276 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.37 |
| ▸ | BID | P55957 | 2/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.36 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15284409 | 0.95 | HCAR2 (0.42) | HCAR2HCAR3KCNH2RARBALDH1A1 | |
| SCHEMBL7579081 | 0.83 | KCNH2 (0.43) | HCAR2HCAR3KCNH2PPARAMEN1 | |
| SCHEMBL28822502 | 0.82 | HCAR2 (0.38) | HCAR2HCAR3ALDH1A1 | |
| SCHEMBL300079 | 0.82 | HCAR2 (0.35) | HCAR2ALDH1A1MEN1KMT2A | |
| SCHEMBL723349 | 0.82 | KCNH2 (0.42) | KCNH2ALDH1A1MEN1KMT2A | |
| SCHEMBL27797675 | 0.79 | IKBKB (0.41) | HCAR2HCAR3KCNH2ALDH1A1MEN1 | |
| Acetic Acid SCHEMBL28946334 | 0.77 | KCNH2 (0.47) | HCAR2HCAR3KCNH2PPARAALDH1A1 | |
| SCHEMBL949054 | 0.77 | HDAC1 (0.44) | PPARAMAPT | |
| SCHEMBL7601602 | 0.77 | KCNH2 (0.46) | HCAR2HCAR3KCNH2ALDH1A1GPR84 | |
| SCHEMBL3638798 | 0.76 | KCNH2 (0.38) | HCAR2HCAR3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0365030-B1 | Imidazole compound and process for preparing the same | ISHIHARA SANGYO KAISHA (JP) | 1994-01-26 | — | — | EP | disclosed |
| US-5023336-A | Fungicides, biocides | ISHIHARA SANGYO KAISHA LTD. (JP) | 1991-06-11 | — | — | US | disclosed |
| EP-0365030-A1 | Imidazole compound and process for preparing the same | ISHIHARA SANGYO KAISHA, Ltd. (JP) | 1990-04-25 | — | — | EP | disclosed |