Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QDPR | P09417 | 2/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 15/20 | 0.49 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.47 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.47 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.47 |
| ▸ | TRPC6 | Q9Y210 | 2/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20522882 | 0.83 | PDE4B (0.56) | QDPRPDE4BTRPC6PDE4APDE4C | |
| SCHEMBL17076795 | 0.82 | QDPR (0.55) | QDPRPDE4BPDE4APDE4CPDE4D | |
| SCHEMBL15653074 | 0.82 | QDPR (0.55) | QDPRPDE4BPDE4APDE4CPDE4D | |
| SCHEMBL15651488 | 0.82 | QDPR (0.55) | QDPRPDE4BPDE4APDE4CPDE4D | |
| SCHEMBL13362034 | 0.81 | QDPR (0.54) | QDPRPDE4BPDE4APDE4CPDE4D | |
| SCHEMBL2227613 | 0.81 | QDPR (0.59) | QDPRPDE4BPDE4APDE4CPDE4D | |
| SCHEMBL3311407 | 0.81 | QDPR (0.74) | QDPRPDE4BTLR7PDE4APDE4C | |
| SCHEMBL310046 | 0.81 | PDE4B (0.62) | QDPRPDE4BPDE4APDE4CPDE4D | |
| SCHEMBL30957975 | 0.81 | PDE4B (0.62) | QDPRPDE4BPDE4APDE4CPDE4D | |
| SCHEMBL13362111 | 0.80 | QDPR (0.55) | QDPRPDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2162454-A1 | IMIDAZOPYRIDINE KINASE INHIBITORS | GlaxoSmithKline LLC (US) | 2010-03-17 | — | — | EP | disclosed |
| WO-2008150799-A1 | IMIDAZOPYRIDINE KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-12-11 | — | — | WO | disclosed |