Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18704062 | 0.89 | KDM4E (0.54) | L3MBTL1KDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL11647730 | 0.82 | ALDH1A1 (0.47) | L3MBTL1KDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL30370553 | 0.80 | KDM4E (0.55) | L3MBTL1KDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL29420807 | 0.80 | KDM4E (0.60) | L3MBTL1KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL534956 | 0.80 | L3MBTL1 (0.57) | L3MBTL1KDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL29496331 | 0.80 | L3MBTL1 (0.57) | L3MBTL1KDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL1140140 | 0.80 | KDM4E (0.71) | KDM4EALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL553686 | 0.80 | KDM4E (0.55) | L3MBTL1KDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL318407 | 0.80 | KDM4E (0.60) | L3MBTL1KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL30411552 | 0.80 | KDM4E (0.71) | KDM4EALDH1A1KMT2AMEN1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025083630-A1 | HETEROAROMATIC COMPOUNDS AS MUSCARINIC M4 RECEPTOR POSITIVE ALLOSTERIC MODULATORS (M4 PAMS) | SUVEN LIFE SCIENCES LIMITED (IN) | 2025-04-24 | — | — | WO | disclosed |
| WO-2025081019-A1 | KIF MODULATOR COMPOUNDS AND METHODS OF USE | IAMBIC THERAPEUTICS, INC. (US) | 2025-04-17 | — | — | WO | disclosed |
| US-10342782-B2 | Positive allosteric modulators of the muscarinic acetylcholine receptor M4 | VANDERBILT UNIVERSITY (US) | 2019-07-09 | — | — | US | disclosed |
| US-10342782-B2 | Positive allosteric modulators of the muscarinic acetylcholine receptor M4 | VANDERBILT UNIVERSITY (US) | 2019-07-09 | — | — | US | disclosed |
| US-20180028501-A1 | POSITIVE ALLOSTERIC MODULATORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 | VANDERBILT UNIVERSITY | 2018-02-01 | — | — | US | disclosed |
| US-20180028501-A1 | POSITIVE ALLOSTERIC MODULATORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 | VANDERBILT UNIVERSITY | 2018-02-01 | — | — | US | disclosed |
| US-20180028501-A1 | POSITIVE ALLOSTERIC MODULATORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 | VANDERBILT UNIVERSITY | 2018-02-01 | — | — | US | disclosed |
| EP-2789606-B1 | Modulators of CFTR | VERTEX PHARMA (US) | 2017-11-15 | — | — | EP | disclosed |
| EP-2789606-B1 | Modulators of CFTR | VERTEX PHARMA (US) | 2017-11-15 | — | — | EP | disclosed |
| US-9725440-B2 | Modulators of CFTR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2017-08-08 | — | — | US | disclosed |
| US-4965346-A | DYEING POLYESTERS | BASF AKTIENGESELLSCHAFT (DE) | 1990-10-23 | — | — | US | disclosed |
| US-4962190-A | PRINTING, DYEING CELLULOSE CONTAINING MATERIAL | BASF AKTIENGESELLSCHAFT (DE) | 1990-10-09 | — | — | US | disclosed |
| EP-0201896-B1 | DYESTUFFS WITH THIOPHENE RESTS | BASF Aktiengesellschaft (DE) | 1990-05-02 | — | — | EP | disclosed |
| US-4855413-A | FOR POLYESTERS AND BLENDS | BASF AKTIENGESELLSCHAFT (DE) | 1989-08-08 | — | — | US | disclosed |
| US-4855412-A | Diaminopyridine azo dyes having acyloxy radicals substituted on the diaminopyridine | BASF AKTIENGESELLSCHAFT (DE) | 1989-08-08 | — | — | US | disclosed |
| EP-0317859-A2 | Azo dyes containing polyethylenimine | BASF Aktiengesellschaft (DE) | 1989-05-31 | — | — | EP | disclosed |
| EP-0281920-A2 | Dyestuffs with N-(2-aminomethyle)-piperazine groups and their use | BASF Aktiengesellschaft (DE) | 1988-09-14 | — | — | EP | disclosed |
| EP-0244740-A2 | Diaminopyridine azo dyes with acyloxy groups | BASF Aktiengesellschaft (DE) | 1987-11-11 | — | — | EP | disclosed |
| EP-0214445-A2 | Heterocyclic azo dyes | BASF Aktiengesellschaft (DE) | 1987-03-18 | — | — | EP | disclosed |
| EP-0201896-A1 | Dyestuffs with thiophene rests | BASF Aktiengesellschaft (DE) | 1986-11-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10342782-B2 | Positive allosteric modulators of the muscarinic acetylcholine receptor M4 | CHRM4, CHRM2, CHRM1 | L3MBTL1 2329/4885KDM4E 940/4885ALDH1A1 3342/4885 |
| US-20180028501-A1 | POSITIVE ALLOSTERIC MODULATORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 | CHRM4, CHRM2, CHRM1 | L3MBTL1 2329/4885KDM4E 940/4885ALDH1A1 3342/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.