Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PREP | P48147 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26537946 | 0.84 | GPR119 (0.41) | CHRM2CHRM1CHRM3HPGDPREP | |
| SCHEMBL5762755 | 0.84 | GPR119 (0.41) | CHRM2CHRM1CHRM3HPGDPREP | |
| SCHEMBL30289320 | 0.81 | HSD17B10 (0.41) | CHRM2CHRM1CHRM3HPGDHSD17B10 | |
| SCHEMBL7958092 | 0.81 | CHRM2 (0.43) | CHRM2CHRM1CHRM3HPGDPREP | |
| SCHEMBL21761369 | 0.81 | CHRM2 (0.43) | CHRM2CHRM1CHRM3HPGDPREP | |
| SCHEMBL3653276 | 0.80 | CHRM2 (0.49) | CHRM2CHRM1CHRM3HPGDPREP | |
| SCHEMBL24421398 | 0.80 | NR1H2 (0.40) | CHRM2CHRM1CHRM3HSD17B10SMN1; SMN2 | |
| SCHEMBL28818824 | 0.80 | CHRM2 (0.37) | CHRM2CHRM1CHRM3HPGDHSD17B10 | |
| SCHEMBL27770742 | 0.80 | CHRM2 (0.37) | CHRM2CHRM1CHRM3HPGDPREP | |
| SCHEMBL28175927 | 0.80 | CHRM2 (0.37) | CHRM2CHRM1CHRM3HPGDPREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2162454-A1 | IMIDAZOPYRIDINE KINASE INHIBITORS | GlaxoSmithKline LLC (US) | 2010-03-17 | — | — | EP | disclosed |
| WO-2008150799-A1 | IMIDAZOPYRIDINE KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-12-11 | — | — | WO | disclosed |
| EP-1789045-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-05-30 | — | — | EP | disclosed |
| WO-2006023400-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-03-02 | — | — | WO | disclosed |