Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.48 |
| ▸ | XDH | P47989 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27483301 | 0.84 | KDM4E (0.38) | KDM4CXDHKDM4EGAAALDH1A1 | |
| SCHEMBL1985820 | 0.84 | KDM4E (0.40) | KDM4CXDHKDM4EGAAALDH1A1 | |
| SCHEMBL28174099 | 0.84 | XDH (0.62) | XDHKDM4EALDH1A1HTTMEN1 | |
| SCHEMBL1979657 | 0.81 | KDM4E (0.43) | XDHKDM4EGAAALDH1A1HPGD | |
| Phosphoric Acid SCHEMBL28087780 | 0.79 | KDM4E (0.37) | XDHKDM4EGAAALDH1A1HPGD | |
| SCHEMBL27275712 | 0.79 | KDM4E (0.41) | XDHKDM4EGAAALDH1A1HPGD | |
| SCHEMBL29150590 | 0.79 | KDM4E (0.41) | XDHKDM4EGAAALDH1A1HPGD | |
| SCHEMBL32686177 | 0.78 | KDM4E (0.40) | KDM4EGAAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL28478046 | 0.78 | KDM4E (0.43) | KDM4EGAAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL1568354 | 0.78 | GAA (0.40) | KDM4EGAAALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2171066-A1 | FORTIFICATION OF PLANTS WITH FOLATES BY METABOLIC ENGINEERING | Universiteit Gent (BE) | 2010-04-07 | — | — | EP | disclosed |
| WO-2009000733-A1 | FORTIFICATION OF PLANTS WITH FOLATES BY METABOLIC ENGINEERING | UNIVERSITEIT GENT (BE) | 2008-12-31 | — | — | WO | disclosed |