Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 3/20 | 0.34 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18486711 | 0.82 | KDM4E (0.38) | KDM4EGAAAKR1B1ALDH1A1SMN1; SMN2 | |
| SCHEMBL27483301 | 0.79 | KDM4E (0.38) | KDM4EGAAALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL3639474 | 0.79 | KDM4C (0.48) | KDM4EGAAALDH1A1SMN1; SMN2HPGD | |
| Pterine SCHEMBL4879287 | 0.74 | AKR1B1 (0.51) | AKR1B1 | |
| SCHEMBL1568354 | 0.73 | GAA (0.40) | KDM4EGAAAKR1B1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1979657 | 0.73 | KDM4E (0.43) | KDM4EGAAALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL28068575 | 0.73 | GAA (0.40) | KDM4EGAAAKR1B1ALDH1A1SMN1; SMN2 | |
| SCHEMBL32686177 | 0.73 | KDM4E (0.40) | KDM4EGAAAKR1B1ALDH1A1SMN1; SMN2 | |
| SCHEMBL28176089 | 0.73 | KDM4E (0.40) | KDM4EGAAAKR1B1ALDH1A1SMN1; SMN2 | |
| SCHEMBL28174099 | 0.73 | XDH (0.62) | KDM4EALDH1A1XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106165175-B | High molecular electrolyte composition and polyelectrolyte membrane, film electrode composite element and the polymer electrolyte fuel cell for using it | 东丽株式会社 | 2019-11-08 | — | — | CN | disclosed |
| CN-106165175-A | High molecular electrolyte composition and use its polyelectrolyte membrane, film electrode composite element and polymer electrolyte fuel cell | 东丽株式会社 | 2016-11-23 | — | — | CN | disclosed |