Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | SLC25A1 | P53007 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7440236 | 0.87 | TSHR (0.48) | TSHRALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL8668862 | 0.87 | ALDH1A1 (0.50) | TSHRALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL30729473 | 0.87 | ALDH1A1 (0.50) | TSHRALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL8063524 | 0.86 | VCAM1 (0.46) | TSHRALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL6534956 | 0.86 | VCAM1 (0.46) | TSHRALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL611879 | 0.85 | ALDH1A1 (0.49) | TSHRALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL30527915 | 0.83 | TDP1 (0.50) | TSHRALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL2728751 | 0.83 | TDP1 (0.50) | TSHRALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL27461738 | 0.83 | DPP4 (0.47) | TSHRALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL27985199 | 0.81 | ALDH1A1 (0.49) | TSHRALDH1A1CYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111943854-B | Synthetic method of 3, 4-dichloro-2-nitrobenzoic acid | 阿里生物新材料（常州）有限公司 | 2022-03-11 | — | — | CN | claimed |
| CN-111943854-A | Synthetic method of 3, 4-dichloro-2-nitrobenzoic acid | 阿里生物新材料（常州）有限公司 | 2020-11-17 | — | — | CN | claimed |
| EP-1016405-A2 | Arylating medicaments | Radopath Pharmaceuticals International Limited (GB) | 2000-07-05 | — | — | EP | claimed |
| EP-0700287-A1 | ARYLATING MEDICAMENTS | RADOPATH LIMITED (GB) | 1996-03-13 | — | — | EP | claimed |
| WO-1994027584-A2 | ARYLATING MEDICAMENTS | RADOPATH LIMITED (GB) | 1994-12-08 | — | — | WO | claimed |
| JP-62106063-A | — | — | None | — | — | JP | disclosed |
| CN-111943854-B | Synthetic method of 3, 4-dichloro-2-nitrobenzoic acid | 阿里生物新材料（常州）有限公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-111943854-B | Synthetic method of 3, 4-dichloro-2-nitrobenzoic acid | 阿里生物新材料（常州）有限公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-111943854-B | Synthetic method of 3, 4-dichloro-2-nitrobenzoic acid | 阿里生物新材料（常州）有限公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-111995581-A | Synthetic method of 5- (trifluoromethoxy) -1H-benzo [ d ] imidazole-2-carboxylic acid | 阿里生物新材料（常州）有限公司 | 2020-11-27 | — | — | CN | disclosed |
| CN-111943854-A | Synthetic method of 3, 4-dichloro-2-nitrobenzoic acid | 阿里生物新材料（常州）有限公司 | 2020-11-17 | — | — | CN | disclosed |
| CN-111943854-A | Synthetic method of 3, 4-dichloro-2-nitrobenzoic acid | 阿里生物新材料（常州）有限公司 | 2020-11-17 | — | — | CN | disclosed |
| EP-2164924-A2 | IMPROVING THE PHOTOSTABILITY AND/OR CONTROL OF THE FLUORESCENCE INTENSITY OF FLUORESCENT DYES | Picoquant GmbH (DE) | 2010-03-24 | — | — | EP | disclosed |
| EP-1737831-A4 | NEUROLOGICALLY-ACTIVE COMPOUNDS | PRANA BIOTECHNOLOGY LTD (AU) | 2009-07-22 | — | — | EP | disclosed |
| WO-2009003948-A2 | PROCESS FOR IMPROVING THE PHOTOSTABILITY AND/OR CONTROL OF THE FLUORESCENCE INTENSITY OF FLUORESCENT DYES | UNIVERSITÄT BIELEFELD (DE) | 2009-01-08 | — | — | WO | disclosed |
| EP-1737831-A1 | NEUROLOGICALLY-ACTIVE COMPOUNDS | Prana Biotechnology Limited (AU) | 2007-01-03 | — | — | EP | disclosed |
| WO-2005095360-A1 | NEUROLOGICALLY-ACTIVE COMPOUNDS | PRANA BIOTECHNOLOGY LIMITED (AU) | 2005-10-13 | — | — | WO | disclosed |
| JP-S62106063-A | PURIFICATION OF 2-CHLORO-4-NITROBENZOIC ACID | DAICEL CHEM IND LTD | 1987-05-16 | — | — | JP | disclosed |
| US-4361436-A | Composition for plant growth regulation | GAF CORPORATION (US) | 1982-11-30 | — | — | US | disclosed |
| US-4328026-A | PLANT GROWTH REGULATORS, ETHYLENE GENERATORS | GAF CORPORATION (US) | 1982-05-04 | — | — | US | disclosed |