Acetone

Acetone

SCHEMBL3639677

CC(=O)CCCCCCCCCCCCCCOc1ccc(C(C)(C)c2ccc(O)cc2)cc1.CC(C)=O

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR5A1 Q13285 1/20 0.50
KDM4E B2RXH2 8/20 0.47
ALDH1A1 P00352 5/20 0.47
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
HTT P42858 1/20 0.47
GAA P10253 1/20 0.46
POLB P06746 2/20 0.45
ESR1 P03372 2/20 0.44
CYP3A4 P08684 1/20 0.44
AR P10275 1/20 0.44
HPGD P15428 1/20 0.44
TSHR P16473 1/20 0.44
SLC6A2 P23975 1/20 0.44
SLC6A4 P31645 1/20 0.44
HTR6 P50406 1/20 0.44
ESRRG P62508 1/20 0.44
SLC6A3 Q01959 1/20 0.44
ESR2 Q92731 1/20 0.44
HSD17B10 Q99714 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3635581 0.99 NR5A1 (0.51) NR5A1KDM4EALDH1A1MEN1KMT2A
SCHEMBL14962788 0.93 KDM4E (0.50) NR5A1KDM4EALDH1A1MEN1KMT2A
SCHEMBL25794749 0.88 NR5A1 (0.62) NR5A1GAATSHRLTA4HL3MBTL1
SCHEMBL25794785 0.88 NR5A1 (0.62) NR5A1GAATSHRLTA4HL3MBTL1
SCHEMBL15887764 0.88 NR5A1 (0.62) NR5A1GAATSHRLTA4HL3MBTL1
SCHEMBL9453956 0.87 NR5A1 (0.51) NR5A1KDM4EALDH1A1MEN1KMT2A
SCHEMBL28925379 0.84 SMN1; SMN2 (0.54) KDM4EALDH1A1MEN1KMT2AGAA
SCHEMBL2947534 0.80 ALDH1A1 (0.67) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL9394712 0.79 NR5A1 (0.74) NR5A1KDM4EALDH1A1MEN1KMT2A
SCHEMBL134271 0.79 ESR1 (0.53) KDM4EALDH1A1MEN1KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2167566-B1 METHOD FOR STORAGE AND/OR TRANSPORT OF BISPHENOLACETONE AND METHOD FOR PRODUCING AROMATIC POLYCARBONATE SHELL INT RESEARCH (NL) 2012-05-16 EP disclosed
EP-2167566-A1 METHOD FOR STORAGE AND/OR TRANSPORT OF BISPHENOLACETONE AND METHOD FOR PRODUCING AROMATIC POLYCARBONATE Shell Internationale Research Maatschappij B.V. (NL) 2010-03-31 EP disclosed
WO-2009010486-A1 METHOD FOR STORAGE AND/OR TRANSPORT OF BISPHENOLACETONE AND METHOD FOR PRODUCING AROMATIC POLYCARBONATE SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2009-01-22 WO disclosed