SCHEMBL134271

SCHEMBL134271

CC(=O)COc1ccc(C(C)(C)c2ccc(O)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.53
ESR2 Q92731 3/20 0.53
CYP3A4 P08684 2/20 0.53
AR P10275 2/20 0.53
HPGD P15428 1/20 0.53
TSHR P16473 1/20 0.53
SLC6A2 P23975 1/20 0.53
SLC6A4 P31645 1/20 0.53
HTR6 P50406 1/20 0.53
ESRRG P62508 1/20 0.53
SLC6A3 Q01959 1/20 0.53
HSD17B10 Q99714 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.51
ALDH1A1 P00352 3/20 0.47
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
KDM4E B2RXH2 3/20 0.44
POLB P06746 1/20 0.44
MEN1 O00255 1/20 0.43
HTT P42858 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9320698 0.88 LTA4H (0.50) ESR1ALDH1A1
SCHEMBL29226853 0.87 SMN1; SMN2 (0.70) ESR1ESR2CYP3A4ARHPGD
SCHEMBL13881558 0.85 SMN1; SMN2 (0.50) ARHPGDTSHRSMN1; SMN2ALDH1A1
SCHEMBL14039496 0.84 SMN1; SMN2 (0.62) ESR1ESR2SMN1; SMN2ALDH1A1
SCHEMBL17364456 0.84 PTGS2 (0.49) SMN1; SMN2ALDH1A1KDM4EPOLBMEN1
SCHEMBL14962788 0.83 KDM4E (0.50) ESR1ESR2CYP3A4ARHPGD
SCHEMBL8219820 0.82 SMN1; SMN2 (0.73) CYP3A4TSHRHSD17B10SMN1; SMN2ALDH1A1
SCHEMBL29226837 0.81 GAA (0.56) ESR1ESR2CYP3A4ARHPGD
SCHEMBL3635581 0.80 NR5A1 (0.51) ESR1ESR2CYP3A4ARHPGD
SCHEMBL29226836 0.80 ESR1 (0.46) ESR1ESR2CYP3A4ARHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2495351-A1 ZINC-COATED STEEL PLATE JFE Steel Corporation (JP) 2012-09-05 EP disclosed
EP-1193563-B1 Toner, method for manufacturing the toner, and image forming method and apparatus using the toner RICOH CO LTD (JP) 2012-03-07 EP disclosed
US-8026032-B2 Carrier, supplemental developer, developer in image developer, developer feeding apparatus, image forming apparatus and process cartridge RICOH COMPANY, LTD. (JP) 2011-09-27 US disclosed
EP-1914598-B1 Image forming apparatus RICOH CO LTD (JP) 2011-08-10 EP disclosed
US-6924073-B2 Toner for developing electrostatic latent image, toner cartridge, developer, developer cartridge, image forming method, and image forming apparatus RICOH COMPANY, LTD. (JP) 2005-08-02 US disclosed
US-6911289-B2 Toner, method for manufacturing the toner, and image forming method and apparatus using the toner RICOH COMPANY LIMITED (JP) 2005-06-28 US disclosed
US-6811944-B2 TONER HAVING A GOOD LOW TEMPERATURE FIXABILITY AND GOOD HIGH TEMPERATURE PRESERVABILITY, WITHOUT CAUSING A FILMING PROBLEM RICOH COMPANY LIMITED (JP) 2004-11-02 US disclosed
US-6813461-B2 Toner, method for manufacturing the toner, and image forming method and apparatus using the toner RICOH COMPANY LIMITED (JP) 2004-11-02 US disclosed
US-20040166429-A1 Toner, method for manufacturing the toner, and image forming method and apparatus using the toner HIGUCHI HIROTO (JP) 2004-08-26 US disclosed
US-20040166428-A1 Toner, method for manufacturing the toner, and image forming method and apparatus using the toner HIGUCHI HIROTO (JP) 2004-08-26 US disclosed
EP-1193563-A1 Toner, method for manufacturing the toner, and image forming method and apparatus using the toner Ricoh Company, Ltd. (JP) 2002-04-03 EP disclosed
EP-0400235-B1 Resins for electrophotographic toner and method for manufacturing the same MITSUI CHEMICALS INC (JP) 1999-03-31 EP disclosed
EP-0375321-B1 Toner composition for electrophotography MITSUI TOATSU CHEMICALS (JP) 1995-06-21 EP disclosed
EP-0256136-B1 TONER COMPOSITION FOR ELECTROPHOTOGRAPHY MITSUI TOATSU CHEMICALS (JP) 1994-06-01 EP disclosed
US-5279915-A Polyesterurethane copolymer MITSUI TOATSU CHEMICALS, INC. (JP) 1994-01-18 US disclosed
US-5037715-A Urethane-modified polyester; storage stable; antifogging and antiblocking agents; good fixing properties MITSUI TOATSU CHEMICALS, INC. (JP) 1991-08-06 US disclosed
US-4981923-A POLYESTERURETHANE MITSUI TOATSU CHEMICALS, INC. (JP) 1991-01-01 US disclosed
EP-0400235-A1 Resins for toner of electrophotogaphy and method for manufacturing the same MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-12-05 EP disclosed
EP-0375321-A2 Toner composition for electrophotography MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-06-27 EP disclosed
US-4833057-A URETHANE MODIFIED POLYESTERS MITSUI TOATSU CHEMICALS, INC. (JP) 1989-05-23 US disclosed