SCHEMBL363982

SCHEMBL363982

CCOC(=O)CCc1ccc(C)cc1

nearest known ligand 0.77

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 2/20 0.77
CYP4A11 Q02928 2/20 0.77
CYP4Z1 Q86W10 3/20 0.59
L3MBTL1 Q9Y468 4/20 0.57
LMNA P02545 2/20 0.57
MAPT P10636 2/20 0.57
TDP1 Q9NUW8 3/20 0.53
FFAR1 O14842 1/20 0.50
HRH3 Q9Y5N1 1/20 0.50
CYP4F11 Q9HBI6 1/20 0.49
CYP4F12 Q9HCS2 1/20 0.49
ALDH1A1 P00352 2/20 0.48
KDM4E B2RXH2 1/20 0.48
SLC5A1 P13866 1/20 0.47
SLC5A2 P31639 1/20 0.47
EPHX2 P34913 1/20 0.47
ALOX5 P09917 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL68902 0.94 CYP4F2 (0.85) CYP4F2CYP4A11CYP4Z1L3MBTL1LMNA
SCHEMBL10289874 0.89 CYP4F2 (0.62) CYP4F2CYP4A11CYP4Z1L3MBTL1LMNA
SCHEMBL879130 0.89 CYP4F2 (0.77) CYP4F2CYP4A11CYP4Z1L3MBTL1LMNA
SCHEMBL10206072 0.89 CYP4F2 (0.77) CYP4F2CYP4A11CYP4Z1L3MBTL1LMNA
SCHEMBL11437256 0.89 CYP4F2 (0.77) CYP4F2CYP4A11CYP4Z1L3MBTL1LMNA
SCHEMBL24988200 0.87 CYP4F2 (0.60) CYP4F2CYP4A11CYP4Z1L3MBTL1LMNA
SCHEMBL14570534 0.87 CYP4Z1 (0.62) CYP4F2CYP4A11CYP4Z1L3MBTL1LMNA
SCHEMBL5543917 0.87 CYP4F2 (0.74) CYP4F2CYP4A11CYP4Z1L3MBTL1LMNA
SCHEMBL4889211 0.87 CYP4F2 (0.80) CYP4F2CYP4A11CYP4Z1L3MBTL1LMNA
SCHEMBL22098222 0.87 CYP4F2 (1.00) CYP4F2CYP4A11CYP4Z1L3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12398089-B2 Method for preparing organic carboxylic ester by using combined catalyst of aryl bidentate phosphine ligand NANJING CHENGZHI CLEAN ENERGY CO. LTD. (CN) 2025-08-26 US disclosed
CN-113461559-B Compound, compound product, preparation method and application 中国人民解放军军事科学院军事医学研究院 2023-08-08 CN disclosed
US-20220298097-A1 METHOD FOR PREPARING ORGANIC CARBOXYLIC ESTER BY USING COMBINED CATALYST OF ARYL BIDENTATE PHOSPHINE LIGAND NANJING CHENGZHI CLEAN ENERGY CO. LTD. (CN) 2022-09-22 US disclosed
CN-111087306-B Method for preparing organic carboxylic ester by aryl bidentate phosphine ligand combined catalysis 南京诚志清洁能源有限公司 2021-08-03 CN disclosed
WO-2021129138-A1 METHOD FOR PREPARING ORGANIC CARBOXYLIC ESTER BY MEANS OF COMBINATORIAL CATALYSIS WITH ARYL BIDENTATE PHOSPHINE LIGAND 南京诚志清洁能源有限公司 2021-07-01 WO disclosed
WO-2021129138-A1 METHOD FOR PREPARING ORGANIC CARBOXYLIC ESTER BY MEANS OF COMBINATORIAL CATALYSIS WITH ARYL BIDENTATE PHOSPHINE LIGAND 南京诚志清洁能源有限公司 2021-07-01 WO disclosed
CN-111087306-A Method for preparing organic carboxylic ester by aryl bidentate phosphine ligand combined catalysis 南京诚志清洁能源有限公司 2020-05-01 CN disclosed
CN-108419435-A Compound and epigenetics for treating cancer 新加坡科技研究局 2018-08-17 CN disclosed
CN-107548397-A Kv1.3 inhibitors and medical uses thereof 4SC股份公司 2018-01-05 CN disclosed
CN-107548396-A Kv1.3 inhibitors and medical uses thereof 4SC股份公司 2018-01-05 CN disclosed
WO-2006004742-A2 α, β-UNSATURATED ESTERS AND ACIDS BY STEREOSELECTIVE DEHYDRATION JANSSEN PHARAMCEUTICA N.V. (BE) 2006-01-12 WO disclosed
EP-1564200-A1 Ketone compounds and compositions for cholesterol management and related uses Esperion Therapeutics Inc. (US) 2005-08-17 EP disclosed
EP-1551826-A1 HYDANTOINE DERIVATIVES AND THEIR USE AS TACE INHIBITORS Astrazeneca AB (SE) 2005-07-13 EP disclosed
EP-0786691-B1 Silver halide light sensitive emulsion layer having enhanced photographic sensitivity EASTMAN KODAK CO (US) 2004-12-29 EP disclosed
WO-2004024721-A1 HYDANTOIN DERIVATIVES UND DEREN VERWENDUNG ALS TACE INHIBITOREN ASTRAZENECA AB (SE) 2004-03-25 WO disclosed
WO-2002030860-A9 KETONE COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES ESPERION THERAPEUTICS INC (US) 2003-02-20 WO disclosed
US-5747236-A FRAGMENTABLE ELECTRON DONOR EASTMAN KODAK COMPANY (US) 1998-05-05 US disclosed
EP-0786691-A1 Silver halide light sensitive emulsion layer having enhanced photographic sensitivity EASTMAN KODAK COMPANY (US) 1997-07-30 EP disclosed
US-5220060-A Reacting ester with carbon monoxide in liquid phase with catalyst system of palladium compound, iodide promoter, proton donor CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) 1993-06-15 US disclosed
US-5008451-A Producing carboxylic anhydrides by reacting a carboxylic ester with carbon monoxide using a phodium catalyst, iodide promoter, proton donor and anhydrous conditions CHEVRON RESEARCH COMPANY (US) 1991-04-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220298097-A1 METHOD FOR PREPARING ORGANIC CARBOXYLIC ESTER BY USING COMBINED CATALYST OF ARYL BIDENTATE PHOSPHINE LIGAND POF1B, ADH1C, OSBP CYP4F2 57/4885CYP4A11 53/4885CYP4Z1 952/4885
US-12398089-B2 Method for preparing organic carboxylic ester by using combined catalyst of aryl bidentate phosphine ligand POF1B, ADH1C, OSBP CYP4F2 57/4885CYP4A11 53/4885CYP4Z1 952/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.