Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.55 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ELANE | P08246 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 3/20 | 0.44 |
| ▸ | CCR2 | P41597 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3638008 | 0.90 | NOD2 (0.53) | NOD2NOD1MAPTELANESMN1; SMN2 | |
| SCHEMBL13560447 | 0.87 | NOD2 (0.43) | NOD2NOD1MAPTELANESMN1; SMN2 | |
| SCHEMBL3033204 | 0.85 | NOD2 (0.51) | NOD2NOD1MAPTELANESMN1; SMN2 | |
| SCHEMBL7878190 | 0.85 | NOD2 (0.57) | NOD2NOD1MAPTELANESMN1; SMN2 | |
| SCHEMBL3640350 | 0.84 | CCR2 (0.50) | NOD2NOD1MAPTELANESMN1; SMN2 | |
| SCHEMBL13560440 | 0.79 | CCR2 (0.39) | NOD2NOD1MAPTELANESMN1; SMN2 | |
| SCHEMBL4421628 | 0.78 | NOD2 (0.60) | NOD2NOD1MAPTELANEALDH1A1 | |
| SCHEMBL4203356 | 0.78 | MAPT (0.59) | NOD2NOD1MAPTELANESMN1; SMN2 | |
| SCHEMBL31383537 | 0.78 | MAPT (0.59) | NOD2NOD1MAPTELANESMN1; SMN2 | |
| SCHEMBL4196083 | 0.77 | NOD2 (0.54) | NOD2NOD1MAPTELANESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2166856-A1 | CHEMICAL COMPOUNDS | GlaxoSmithKline LLC (US) | 2010-03-31 | — | — | EP | disclosed |
| WO-2008154271-A1 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-12-18 | — | — | WO | disclosed |