Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | FBP1 | P09467 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3640368 | 1.00 | PTGS1 (0.47) | PTGS1PTGS2ALOX5TTRALDH1A1 | |
| SCHEMBL3668138 | 0.82 | CSNK2A1 (0.50) | PTGS1PTGS2ALOX5TTRMEN1 | |
| SCHEMBL3634451 | 0.81 | MEN1 (0.40) | PTGS1PTGS2ALOX5TTRALDH1A1 | |
| SCHEMBL3634455 | 0.81 | MEN1 (0.40) | PTGS1PTGS2ALOX5TTRALDH1A1 | |
| SCHEMBL7715071 | 0.78 | TSHR (0.52) | ALDH1A1TSHRAKR1C3L3MBTL1MEN1 | |
| SCHEMBL17967354 | 0.77 | MAPT (0.43) | ALDH1A1TSHRAKR1C3L3MBTL1MEN1 | |
| SCHEMBL17967356 | 0.77 | MAPT (0.43) | ALDH1A1TSHRAKR1C3L3MBTL1MEN1 | |
| SCHEMBL3727269 | 0.77 | TSHR (0.39) | PTGS1PTGS2ALOX5TTRALDH1A1 | |
| SCHEMBL4540285 | 0.77 | TSHR (0.39) | PTGS1PTGS2ALOX5TTRALDH1A1 | |
| SCHEMBL6546334 | 0.76 | NFE2L2 (0.55) | PTGS1PTGS2ALOX5TTRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2162518-A1 | LUBRICANT COMPOSITIONS STABILIZED WITH STYRENATED PHENOLIC ANTIOXIDANT | CHEMTURA CORPORATION (US) | 2010-03-17 | — | — | EP | disclosed |
| WO-2009009293-A1 | LUBRICANT COMPOSITIONS STABILIZED WITH STYRENATED PHENOLIC ANTIOXIDANT | CHEMTURA CORPORATION (US) | 2009-01-15 | — | — | WO | disclosed |
| US-20090011961-A1 | Lubricant compositions stabilized with styrenated phenolic antioxidant | CROMPTON HOLDING CORPORATION | 2009-01-08 | — | — | US | disclosed |