Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.39 |
| ▸ | NQO2 | P16083 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | RARA | P10276 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 1/20 | 0.36 |
| ▸ | RARG | P13631 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3634455 | 1.00 | MEN1 (0.40) | MEN1KMT2APTGS2PTGS1NQO2 | |
| SCHEMBL3669752 | 0.84 | TRPA1 (0.46) | MEN1KMT2AALDH1A1TSHRAKR1C3 | |
| SCHEMBL3727269 | 0.83 | TSHR (0.39) | MEN1KMT2APTGS2PTGS1ALDH1A1 | |
| SCHEMBL4540285 | 0.83 | TSHR (0.39) | MEN1KMT2APTGS2PTGS1ALDH1A1 | |
| SCHEMBL3640372 | 0.81 | PTGS1 (0.47) | MEN1KMT2APTGS2PTGS1NQO2 | |
| SCHEMBL3640368 | 0.81 | PTGS1 (0.47) | MEN1KMT2APTGS2PTGS1NQO2 | |
| SCHEMBL9417061 | 0.75 | ALOX5 (0.40) | MEN1KMT2APTGS2PTGS1ALDH1A1 | |
| SCHEMBL6546872 | 0.74 | MEN1 (0.47) | MEN1KMT2AALDH1A1TSHRAKR1C3 | |
| SCHEMBL6120361 | 0.74 | MEN1 (0.47) | MEN1KMT2AALDH1A1TSHRAKR1C3 | |
| SCHEMBL6546875 | 0.74 | ESR1 (0.50) | MEN1KMT2APTGS2PTGS1NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2162518-A1 | LUBRICANT COMPOSITIONS STABILIZED WITH STYRENATED PHENOLIC ANTIOXIDANT | CHEMTURA CORPORATION (US) | 2010-03-17 | — | — | EP | disclosed |
| WO-2009009293-A1 | LUBRICANT COMPOSITIONS STABILIZED WITH STYRENATED PHENOLIC ANTIOXIDANT | CHEMTURA CORPORATION (US) | 2009-01-15 | — | — | WO | disclosed |
| US-20090011961-A1 | Lubricant compositions stabilized with styrenated phenolic antioxidant | CROMPTON HOLDING CORPORATION | 2009-01-08 | — | — | US | disclosed |