Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.51 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.41 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29668422 | 1.00 | TYR (0.51) | TYRTRPA1TSHRERCC1ERCC4 | |
| SCHEMBL51701 | 0.86 | TRPA1 (0.59) | TRPA1TSHRMAPTLMNAESR1 | |
| SCHEMBL3638975 | 0.85 | GABRA1 (0.53) | TYRTRPA1TSHRERCC1ERCC4 | |
| SCHEMBL6054819 | 0.85 | TRPA1 (0.50) | TYRTRPA1TSHRMAPTLMNA | |
| SCHEMBL51302 | 0.85 | TRPA1 (0.50) | TYRTRPA1TSHRERCC1ERCC4 | |
| SCHEMBL11414960 | 0.84 | TYR (0.46) | TYRHTR2AOPRK1GAAHTT | |
| SCHEMBL28318580 | 0.83 | KAT8 (0.50) | TYRLMNAESR1HTR2ASLC6A4 | |
| SCHEMBL3640374 | 0.83 | TYR (0.50) | TYRTRPA1TSHRLMNAESR1 | |
| SCHEMBL11881888 | 0.82 | KAT8 (0.52) | LMNAESR1CHRM2CHRM5CHRM1 | |
| SCHEMBL3111015 | 0.82 | KAT8 (0.52) | LMNAESR1CHRM2CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114635047-B | Method for extracting cesium in salt lake brine | 中国科学院过程工程研究所 | 2023-05-23 | — | — | CN | claimed |
| CN-114635047-A | Method for extracting cesium in salt lake brine | 中国科学院过程工程研究所 | 2022-06-17 | — | — | CN | claimed |
| CN-104130108-A | Synthetic method for novel rubidium extractant 4-ethyl-2(alpha-methylbenzyl)phenol | UNIV CHENGDU TECHNOLOGY | 2014-11-05 | — | — | CN | claimed |
| CN-114635047-B | Method for extracting cesium in salt lake brine | 中国科学院过程工程研究所 | 2023-05-23 | — | — | CN | disclosed |
| CN-104130108-B | A kind of rubidium extraction agent 4-ethyl-2(α-methylbenzyl) synthetic method of phenol | CHENGDU UNIVERSITY OF TECHNOLOGY (CN) | 2016-04-06 | — | — | CN | disclosed |
| CN-104130108-B | A kind of rubidium extraction agent 4-ethyl-2(α-methylbenzyl) synthetic method of phenol | CHENGDU UNIVERSITY OF TECHNOLOGY (CN) | 2016-04-06 | — | — | CN | disclosed |
| CN-104130108-A | Synthetic method for novel rubidium extractant 4-ethyl-2(alpha-methylbenzyl)phenol | UNIV CHENGDU TECHNOLOGY | 2014-11-05 | — | — | CN | disclosed |
| CN-104130108-A | Synthetic method for novel rubidium extractant 4-ethyl-2(alpha-methylbenzyl)phenol | UNIV CHENGDU TECHNOLOGY | 2014-11-05 | — | — | CN | disclosed |
| CN-104130108-A | Synthetic method for novel rubidium extractant 4-ethyl-2(alpha-methylbenzyl)phenol | UNIV CHENGDU TECHNOLOGY | 2014-11-05 | — | — | CN | disclosed |
| CN-101966399-A | Synergic extractant for extracting rubidium salt from brine and extraction method thereof | QINGHAI INST SALT LAKES CAS | 2011-02-09 | — | — | CN | disclosed |
| EP-2162518-A1 | LUBRICANT COMPOSITIONS STABILIZED WITH STYRENATED PHENOLIC ANTIOXIDANT | CHEMTURA CORPORATION (US) | 2010-03-17 | — | — | EP | disclosed |
| US-20090011961-A1 | Lubricant compositions stabilized with styrenated phenolic antioxidant | CROMPTON HOLDING CORPORATION | 2009-01-08 | — | — | US | disclosed |
| US-20070037812-A1 | Such as 3-{4-[3-(4-Chloro-2- phenoxy-phenoxy)- phenoxy]-2-methyl- phenyl}-propionic acid; peroxisome proliferator activated receptor (PPAR); syndrome X, type II diabetes, hyperglycemia, hyperlipidemia, obesity, coagaulopathy, hypertension, arteriosclerosis | ELI LILLY AND COMPANY (US) | 2007-02-15 | — | — | US | disclosed |
| US-20060257987-A1 | Ppar modulators | ELI LILLY AND COMPANY | 2006-11-16 | — | — | US | disclosed |
| EP-1675814-A1 | PHENOXYETHER DERIVATIVES AS PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2006-07-05 | — | — | EP | disclosed |
| EP-1660428-A1 | PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005037763-A1 | PHENOXYETHER DERIVATIVES AS PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-04-28 | — | — | WO | disclosed |
| WO-2005019151-A1 | PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-03-03 | — | — | WO | disclosed |
| US-4950810-A | Selective process for preparting 2,4- or 3,6-di-substituted phenol compounds | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-08-21 | — | — | US | disclosed |
| EP-0335674-A2 | Selective process for preparing 2,4- or 3,6-di-substituted phenol compounds | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1989-10-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070037812-A1 | Such as 3-{4-[3-(4-Chloro-2- phenoxy-phenoxy)- phenoxy]-2-methyl- phenyl}-propionic acid; peroxisome proliferator activated receptor (PPAR); syndrome X, type II diabetes, hyperglycemia, hyperlipidemia, obesity, coagaulopathy, hypertension, arteriosclerosis | PPARA, PPARG, PPARD | TYR 4002/4885TRPA1 2463/4885TSHR 2621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.