Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2292207 | 0.90 | KMT2A (0.46) | LMNAKMT2AMEN1 | |
| SCHEMBL2291225 | 0.88 | LMNA (0.50) | LMNAPOLBPTPN11KMT2AMEN1 | |
| SCHEMBL2297393 | 0.84 | LMNA (0.52) | LMNAPOLBKMT2AMEN1 | |
| SCHEMBL2293210 | 0.83 | GAA (0.50) | LMNAPTPN11KMT2AMEN1 | |
| SCHEMBL2290518 | 0.82 | KMT2A (0.47) | LMNAKMT2AMEN1 | |
| SCHEMBL2291401 | 0.81 | KMT2A (0.51) | LMNAKMT2A | |
| SCHEMBL2291154 | 0.79 | MEN1 (0.50) | LMNAKMT2AMEN1 | |
| SCHEMBL2295296 | 0.79 | NAMPT (0.48) | LMNAKMT2AMEN1 | |
| SCHEMBL2296022 | 0.78 | KMT2A (0.45) | LMNAKMT2AMEN1 | |
| SCHEMBL2293920 | 0.78 | NAMPT (0.51) | LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2164326-A1 | AMIDE COMPOUNDS AND THE USE THEREOF | Euro-Celtique, S.A. (LU) | 2010-03-24 | — | — | EP | disclosed |
| WO-2008150447-A1 | AMIDE COMPOUNDS AND THE USE THEREOF | EURO-CELTIQUE S.A. (LU) | 2008-12-11 | — | — | WO | disclosed |