Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2288939 | 0.83 | RAB9A (0.49) | RAB9ASMN1; SMN2GAAALDH1A1NPC1 | |
| SCHEMBL2292999 | 0.80 | RAB9A (0.56) | RAB9ASMN1; SMN2GAAALDH1A1NPC1 | |
| SCHEMBL2291227 | 0.77 | HPGDS (0.53) | SMN1; SMN2ALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL2294293 | 0.77 | GRIN2B (0.50) | RAB9ASMN1; SMN2GAAALDH1A1MAPT | |
| SCHEMBL2294464 | 0.76 | TRPV1 (0.44) | RAB9ASMN1; SMN2GAAALDH1A1NPC1 | |
| SCHEMBL2294335 | 0.76 | RAB9A (0.58) | RAB9ASMN1; SMN2GAAALDH1A1MAPT | |
| SCHEMBL2292429 | 0.73 | MEN1 (0.50) | RAB9ASMN1; SMN2GAAALDH1A1NPC1 | |
| SCHEMBL22218903 | 0.72 | KMT2A (0.73) | RAB9ASMN1; SMN2GAAALDH1A1NPC1 | |
| SCHEMBL2292379 | 0.71 | TSHR (0.50) | SMN1; SMN2GAAALDH1A1MAPTKMT2A | |
| SCHEMBL2293229 | 0.71 | SCN9A (0.49) | SMN1; SMN2GAAALDH1A1KMT2AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2164326-A1 | AMIDE COMPOUNDS AND THE USE THEREOF | Euro-Celtique, S.A. (LU) | 2010-03-24 | — | — | EP | disclosed |
| WO-2008150447-A1 | AMIDE COMPOUNDS AND THE USE THEREOF | EURO-CELTIQUE S.A. (LU) | 2008-12-11 | — | — | WO | disclosed |