Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 1/20 | 0.36 |
| ▸ | SLC6A11 | P48066 | 5/20 | 0.35 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.35 |
| ▸ | ST6GAL1 | P15907 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.32 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.32 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.31 |
| ▸ | NT5E | P21589 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3672713 | 0.83 | DUT (0.38) | TYMPSLC6A11SLC6A1SLC6A12MEN1 | |
| SCHEMBL4074704 | 0.77 | TYMP (0.33) | TYMPSLC6A11SLC6A1LMNATHRB | |
| SCHEMBL3670824 | 0.74 | DUT (0.37) | TYMPSLC6A11SLC6A1SLC6A12MEN1 | |
| SCHEMBL1739171 | 0.74 | TYMP (0.47) | TYMPSLC6A11SLC6A1ST6GAL1LMNA | |
| SCHEMBL5710025 | 0.74 | TYMP (0.62) | TYMPST6GAL1LMNATHRBMTOR | |
| SCHEMBL16144282 | 0.73 | PDE4D (0.34) | TYMPST6GAL1LMNATHRBMTOR | |
| SCHEMBL16144281 | 0.72 | PDE3A (0.36) | TYMPST6GAL1LMNATHRBMTOR | |
| SCHEMBL16144603 | 0.72 | TYMP (0.33) | TYMPST6GAL1LMNATHRBMTOR | |
| SCHEMBL21065502 | 0.72 | TYMP (0.41) | TYMPSLC6A11SLC6A1ST6GAL1LMNA | |
| SCHEMBL1737308 | 0.72 | TYMP (0.54) | TYMPST6GAL1LMNATHRBMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2173760-A2 | CARBOCYCLIC BICYCLIC NUCLEIC ACID ANALOGS | Isis Pharmaceuticals, Inc. (US) | 2010-04-14 | — | — | EP | disclosed |
| WO-2008154401-A2 | CARBOCYCLIC BICYCLIC NUCLEIC ACID ANALOGS | ISIS PHARMACEUTICALS, INC. (US) | 2008-12-18 | — | — | WO | disclosed |