Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 5/20 | 0.38 |
| ▸ | SLC6A11 | P48066 | 5/20 | 0.35 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.35 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.35 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.35 |
| ▸ | TYMP | P19971 | 1/20 | 0.35 |
| ▸ | NT5E | P21589 | 1/20 | 0.34 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.32 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3670824 | 0.91 | DUT (0.37) | DUTSLC6A11SLC6A1P2RY6P2RY14 | |
| SCHEMBL3640871 | 0.83 | TYMP (0.36) | SLC6A11SLC6A1TYMPNT5ESLC6A12 | |
| SCHEMBL31201516 | 0.79 | P2RY14 (0.41) | DUTP2RY6P2RY14TYMPNT5E | |
| SCHEMBL1096814 | 0.79 | P2RY6 (0.38) | DUTSLC6A11SLC6A1P2RY6P2RY14 | |
| SCHEMBL1098282 | 0.79 | P2RY6 (0.38) | DUTSLC6A11SLC6A1P2RY6P2RY14 | |
| SCHEMBL4074748 | 0.79 | P2RY6 (0.38) | DUTSLC6A11SLC6A1P2RY6P2RY14 | |
| SCHEMBL7096692 | 0.78 | P2RY6 (0.41) | DUTSLC6A11SLC6A1P2RY6P2RY14 | |
| SCHEMBL12386210 | 0.78 | P2RY6 (0.41) | DUTSLC6A11SLC6A1P2RY6P2RY14 | |
| SCHEMBL4075035 | 0.78 | NT5E (0.40) | DUTSLC6A11SLC6A1P2RY6P2RY14 | |
| SCHEMBL31201540 | 0.76 | DUT (0.36) | DUTSLC6A11SLC6A1P2RY6P2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2173760-A2 | CARBOCYCLIC BICYCLIC NUCLEIC ACID ANALOGS | Isis Pharmaceuticals, Inc. (US) | 2010-04-14 | — | — | EP | disclosed |
| WO-2008154401-A2 | CARBOCYCLIC BICYCLIC NUCLEIC ACID ANALOGS | ISIS PHARMACEUTICALS, INC. (US) | 2008-12-18 | — | — | WO | disclosed |