Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11119361 | 0.82 | — | — | |
| SCHEMBL21276837 | 0.82 | — | — | |
| SCHEMBL8410506 | 0.80 | LMNA (0.37) | NOS1 | |
| SCHEMBL1921995 | 0.77 | — | — | |
| SCHEMBL504341 | 0.75 | — | — | |
| Methane SCHEMBL11045573 | 0.75 | — | — | |
| SCHEMBL1894944 | 0.75 | — | — | |
| SCHEMBL27383844 | 0.75 | — | — | |
| SCHEMBL11883804 | 0.66 | — | — | |
| SCHEMBL2789898 | 0.66 | NOS3 (0.34) | NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007108004-A2 | S-ALKYLISOTHIOURONIUM DERIVATIVES FOR THE TREATMENT OF INFLAMMATORY DISEASES | MEDITOR PHARMACEUTICALS LTD. (IL) | 2007-09-27 | — | — | WO | claimed |
| EP-2167050-A1 | TASTE MASKED PHARMACEUTICAL COMPOSITIONS OF S-ALKYLISOTHIOURONIUM DERIVATIVES | Meditor Pharmaceuticals Ltd. (IL) | 2010-03-31 | — | — | EP | disclosed |
| WO-2008152619-A1 | TASTE MASKED PHARMACEUTICAL COMPOSITIONS OF S-ALKYLISOTHIOURONIUM DERIVATIVES | MEDITOR PHARMACEUTICALS LTD. (IL) | 2008-12-18 | — | — | WO | disclosed |
| EP-1315505-A4 | PHARMACEUTICAL COMPOSITIONS FOR HEADACHE, MIGRAINE, NAUSEA AND EMESIS | MEDITOR PHARMACEUTICALS LTD (IL) | 2006-02-22 | — | — | EP | disclosed |
| EP-1315505-A2 | PHARMACEUTICAL COMPOSITIONS FOR HEADACHE, MIGRAINE, NAUSEA AND EMESIS | Meditor Pharmaceuticals Ltd. (IL) | 2003-06-04 | — | — | EP | disclosed |
| WO-2002019961-A2 | PHARMACEUTICAL COMPOSITIONS FOR HEADACHE, MIGRAINE, NAUSEA AND EMESIS | MEDITOR PHARMACEUTICALS LTD. (IL) | 2002-03-14 | — | — | WO | disclosed |