SCHEMBL3640941

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3755039	0.79	PARP1 (0.51)	KDM4EHTTLMNAL3MBTL1MEN1
	SCHEMBL9919058	0.79	L3MBTL1 (0.59)	KDM4EL3MBTL1MEN1KMT2APARP1
	SCHEMBL3723803	0.79	SCD (0.54)	KMT2APARP1RAB9ASCD
	SCHEMBL24754380	0.76	PARP1 (0.44)	KDM4EHTTLMNAL3MBTL1MEN1
	SCHEMBL24754381	0.76	DDR1 (0.54)	KMT2APARP1RAB9ASCD
	SCHEMBL258690	0.74	KDM4E (0.54)	KDM4EHTTMEN1KMT2AALDH1A1
	SCHEMBL11397210	0.73	KDM4E (0.42)	KDM4EHTTLMNAL3MBTL1MEN1
	SCHEMBL11086450	0.73	KDM4E (0.42)	KDM4EHTTLMNAL3MBTL1MEN1
	SCHEMBL30553041	0.73	MAPT (0.47)	KMT2AMAPTALDH1A1RAB9ASCD
	SCHEMBL6258585	0.72	KDM4E (0.50)	KDM4EHTTLMNAL3MBTL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.