Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | USP5 | P45974 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3636921 | 0.78 | RAB9A (0.57) | KDM4EHPGDHSD17B10USP5RAB9A | |
| SCHEMBL6972582 | 0.76 | KDM4E (0.54) | KDM4EHPGDHSD17B10USP5RAB9A | |
| SCHEMBL122167 | 0.76 | ACVR1 (0.61) | KDM4EHPGDHSD17B10USP5RAB9A | |
| SCHEMBL3190592 | 0.76 | KDM4E (0.54) | KDM4EHPGDHSD17B10USP5RAB9A | |
| SCHEMBL16181504 | 0.76 | KDM4E (0.54) | KDM4EHPGDHSD17B10USP5RAB9A | |
| SCHEMBL30743619 | 0.76 | KDM4E (0.54) | KDM4EHPGDHSD17B10USP5RAB9A | |
| SCHEMBL29723028 | 0.76 | ACVR1 (0.61) | KDM4EHPGDHSD17B10USP5RAB9A | |
| SCHEMBL28248362 | 0.76 | RAB9A (0.56) | KDM4EHPGDHSD17B10USP5RAB9A | |
| SCHEMBL22021641 | 0.76 | KDM4E (0.54) | KDM4EHPGDHSD17B10USP5RAB9A | |
| SCHEMBL6773633 | 0.76 | USP5 (0.56) | KDM4EHPGDHSD17B10USP5RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 316 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210128777-A1 | ADDITIVE ABLE TO PROVIDE UNDERWATER ADHESION | BAXTER HEALTHCARE SA (CH) | 2021-05-06 | — | — | US | claimed |
| US-8524898-B2 | Proton acceptor iminium/carbocation-type coupling agents | LUXEMBOURG BIO TECHNOLOGIES LTD. (IL) | 2013-09-03 | — | — | US | claimed |
| US-8303973-B2 | Multifunctional compounds for forming crosslinked biomaterials and methods of preparation and use | ANGIOTECH PHARMACEUTICALS (US), INC. (US) | 2012-11-06 | — | — | US | claimed |
| US-20100144588-A1 | PROTON ACCEPTOR IMINIUM/CARBOCATION-TYPE COUPLING AGENTS | LUXEMBOURG BIO TECHNOLOGIES LTD. (IL) | 2010-06-10 | — | — | US | claimed |
| EP-2170822-A2 | PROTON ACCEPTOR IMINIUM/CARBOCATION-TYPE COUPLING AGENTS | Luxembourg Bio Technologies Ltd. (IL) | 2010-04-07 | — | — | EP | claimed |
| WO-2009138985-A2 | COUPLING AGENTS FOR THE SYNTHESIS OF POLYPEPTIDES AND POLYNUCLEOTIDES | LUXEMBOURG BIO TECHNOLOGIES LTD. (IL) | 2009-11-19 | — | — | WO | claimed |
| US-20080312315-A1 | Multifunctional Compounds for Forming Crosslinked Biomaterials and Methods of Preparation and Use | ANGIOTECH PHARMACEUTICALS(US),INC. (US) | 2008-12-18 | — | — | US | claimed |
| WO-2008139481-A2 | PROTON ACCEPTOR IMINIUM/CARBOCATION-TYPE COUPLING AGENTS | LUXEMBOURG BIO TECHNOLOGIES LTD. (IL) | 2008-11-20 | — | — | WO | claimed |
| EP-1796602-A2 | MULTIFUNCTIONAL COMPOUNDS FOR FORMING CROSSLINKED BIOMATERIALS AND METHODS OF PREPARATION AND USE | Angiotech Pharmaceuticals (US), Inc. (US) | 2007-06-20 | — | — | EP | claimed |
| WO-2006083260-A2 | COMPOSITIONS AND SYSTEMS FOR FORMING CROSSLINKED BIOMATERIALS AND ASSOCIATED METHODS OF PREPARATION AND USE | ANGIOTECH BIOMATERIALS CORPORATION (US) | 2006-08-10 | — | — | WO | claimed |
| US-20050281883-A1 | Compositions and systems for forming crosslinked biomaterials and associated methods of preparation and use | ANGIODEVICE INTERNATIONAL GMBH (CH) | 2005-12-22 | — | — | US | claimed |
| EP-0611774-B1 | Production of amides and peptides without racemization in the presence of catalytic amounts of a N-hydroxy-compound | HOFFMANN LA ROCHE (CH) | 1999-05-26 | — | — | EP | claimed |
| US-5750649-A | REACTING ACID AND AMINE IN PRESENCE OF CARBODIIMIDE DEHYDRATING AGENT AND N-HYDROXY COMPOUND; PEPTIDES | HOFFMANN-LA ROCHE INC. (US) | 1998-05-12 | — | — | US | claimed |
| CN-1035873-C | Preparation of amides and peptides | HOFFMANN LA ROCHE (CH) | 1997-09-17 | — | — | CN | claimed |
| US-5536816-A | Process for producing amides using catalytic amounts of an N-hydroxy compound | HOFFMANN-LA ROCHE INC. (US) | 1996-07-16 | — | — | US | claimed |
| CN-1111237-A | Preparation of amides and peptides | HOFFMANN LA ROCHE (CH) | 1995-11-08 | — | — | CN | claimed |
| EP-0611774-A1 | Production of amides and peptides without racemization in the presence of catalytic amounts of a N-hydroxy-compound | F. HOFFMANN-LA ROCHE AG (CH) | 1994-08-24 | — | — | EP | claimed |
| EP-0073912-B1 | OXO-QUINAZOLINE-(THIONO)-PHOSPHORIC(PHOSPHONIC)-ACID ESTERS OR AMIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PESTICIDES | BAYER AG (DE) | 1985-03-20 | — | — | EP | claimed |
| EP-0101902-A1 | Oxoquinazoline-carbamic-acid ester | BAYER AG (DE) | 1984-03-07 | — | — | EP | claimed |
| EP-0073912-A1 | Oxo-quinazoline-(thiono)-phosphoric(phosphonic)-acid esters or amides, process for their preparation and their use as pesticides | BAYER AG (DE) | 1983-03-16 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144588-A1 | PROTON ACCEPTOR IMINIUM/CARBOCATION-TYPE COUPLING AGENTS | PHAX, GIPR, IAPP | KDM4E 4871/4885HPGD 898/4885HSD17B10 3915/4885 |
| US-20050281883-A1 | Compositions and systems for forming crosslinked biomaterials and associated methods of preparation and use | ILK, FN1, MMP1 | KDM4E 3657/4885HPGD 1046/4885HSD17B10 3973/4885 |
| US-20080312315-A1 | Multifunctional Compounds for Forming Crosslinked Biomaterials and Methods of Preparation and Use | ILK, PLOD3, MMP1 | KDM4E 3108/4885HPGD 628/4885HSD17B10 4080/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.