Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LPO | P22079 | 4/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL1223456 | 1.00 | ACHE (0.40) | ACHELMNAHPGDHTTSMN1; SMN2 | |
| Bicarbonate SCHEMBL28771600 | 0.93 | LMNA (0.41) | ACHELMNAHPGDHTTSMN1; SMN2 | |
| Succinic Acid SCHEMBL1305654 | 0.90 | ACHE (0.38) | ACHELMNAHPGDHTTSMN1; SMN2 | |
| SCHEMBL486840 | 0.88 | ACHE (0.40) | ACHELMNAHPGDHTTSMN1; SMN2 | |
| L-Lactic Acid SCHEMBL1331542 | 0.87 | ACHE (0.42) | ACHELMNAHPGDHTTSMN1; SMN2 | |
| SCHEMBL28394690 | 0.87 | ACHE (0.47) | ACHELMNAHPGDHTTSMN1; SMN2 | |
| SCHEMBL294564 | 0.87 | — | — | |
| Acetic Acid SCHEMBL28811877 | 0.86 | CA1 (0.38) | ACHELMNAHPGDHTTSMN1; SMN2 | |
| Iodide SCHEMBL2037554 | 0.85 | ACHE (0.46) | ACHELMNAHPGDHTTSMN1; SMN2 | |
| Hydrogen Sulfide SCHEMBL16760610 | 0.85 | ACHE (0.46) | ACHELMNAHPGDHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0458502-B1 | Latent catalysts, cure-inhibited epoxy resin compositions and laminates prepared therefrom | DOW GLOBAL TECHNOLOGIES INC (US) | 2003-06-18 | — | — | EP | claimed |
| US-5169473-A | Complex of an onium, arsenic or amine compound and boric acid; advanced polyepoxides; storage stability | THE DOW CHEMICAL COMPANY (US) | 1992-12-08 | — | — | US | claimed |
| EP-0458502-A2 | Latent catalysts, cure-inhibited epoxy resin compositions and laminates prepared therefrom | THE DOW CHEMICAL COMPANY (US) | 1991-11-27 | — | — | EP | claimed |
| EP-2158248-B1 | CATALYST FOR CURING EPOXIDES | BASF SE (DE) | 2012-08-15 | — | — | EP | disclosed |
| CN-101754993-A | catalyst for curing epoxides | BASF SE | 2010-06-23 | — | — | CN | disclosed |
| EP-2158248-A1 | CATALYST FOR CURING EPOXIDES | Basf Se (DE) | 2010-03-03 | — | — | EP | disclosed |
| WO-2008152003-A1 | CATALYST FOR CURING EPOXIDES | BASF SE (DE) | 2008-12-18 | — | — | WO | disclosed |
| EP-0458502-B1 | Latent catalysts, cure-inhibited epoxy resin compositions and laminates prepared therefrom | DOW GLOBAL TECHNOLOGIES INC (US) | 2003-06-18 | — | — | EP | disclosed |
| EP-0328020-B1 | Use of a catalyst in epoxy compositions | DOW CHEMICAL CO (US) | 1996-10-09 | — | — | EP | disclosed |
| US-5407977-A | Anhydrous mixtures containing protic organic solvents and methoxy acetone with curing agents, catalysts and/or inhibitors for epoxy and polyepoxy resins | THE DOW CHEMICAL COMPANY (US) | 1995-04-18 | — | — | US | disclosed |
| EP-0639599-A1 | Solvent system and epoxy resin composition | THE DOW CHEMICAL COMPANY (US) | 1995-02-22 | — | — | EP | disclosed |
| US-5342865-A | Solvent system | THE DOW CHEMICAL COMPANY (US) | 1994-08-30 | — | — | US | disclosed |
| EP-0567248-A1 | Solvent system | THE DOW CHEMICAL COMPANY (US) | 1993-10-27 | — | — | EP | disclosed |
| EP-0553887-A2 | Catalysts and epoxy resin composition containing the same | THE DOW CHEMICAL COMPANY (US) | 1993-08-04 | — | — | EP | disclosed |
| US-5169473-A | Complex of an onium, arsenic or amine compound and boric acid; advanced polyepoxides; storage stability | THE DOW CHEMICAL COMPANY (US) | 1992-12-08 | — | — | US | disclosed |
| EP-0458502-A2 | Latent catalysts, cure-inhibited epoxy resin compositions and laminates prepared therefrom | THE DOW CHEMICAL COMPANY (US) | 1991-11-27 | — | — | EP | disclosed |
| US-4925901-A | STORAGE STAABILITY, ONIUM ION CATALYST | THE DOW CHEMICAL COMPANY (US) | 1990-05-15 | — | — | US | disclosed |
| EP-0328020-A2 | Use of a catalyst in epoxy compositions | THE DOW CHEMICAL COMPANY (US) | 1989-08-16 | — | — | EP | disclosed |