Ethyl Acetate

Ethyl Acetate

SCHEMBL364396

CCOC(=O)OC(C)C.CCOC(C)=O

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.61
LMNA P02545 3/20 0.61
HSD17B10 Q99714 1/20 0.61
TSHR P16473 4/20 0.48
SOAT1 P35610 1/20 0.46
ALOX15 P16050 1/20 0.36
MGAM O43451 1/20 0.36
GAA P10253 1/20 0.36
SI P14410 1/20 0.36
MGAM2 Q2M2H8 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
MAPT P10636 1/20 0.34
KDM4E B2RXH2 1/20 0.33
PKM P14618 1/20 0.33
TRPA1 O75762 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL187616 0.91
Ethyl Acetate SCHEMBL28705165 0.89 ALDH1A1 (0.58) ALDH1A1LMNAHSD17B10TSHRSOAT1
Ethyl Acetate SCHEMBL1528836 0.86 ALDH1A1 (0.67) ALDH1A1LMNAHSD17B10TSHRSOAT1
SCHEMBL15259621 0.84 ALDH1A1 (0.65) ALDH1A1LMNAHSD17B10TSHRSOAT1
Ethyl Acetate SCHEMBL28072193 0.83 ALDH1A1 (0.61) ALDH1A1LMNAHSD17B10TSHRSOAT1
SCHEMBL14781530 0.83 ALDH1A1 (0.56) ALDH1A1LMNAHSD17B10TSHRSOAT1
SCHEMBL18256779 0.83 ALDH1A1 (0.50) ALDH1A1LMNAHSD17B10TSHRSOAT1
Ethyl Acetate SCHEMBL364395 0.82 ALDH1A1 (0.67) ALDH1A1LMNAHSD17B10TSHRSOAT1
Ethyl Acetate SCHEMBL5454486 0.81 ALDH1A1 (0.82) ALDH1A1LMNAHSD17B10TSHRSOAT1
Ethyl Acetate SCHEMBL28861856 0.81 ALDH1A1 (0.58) ALDH1A1LMNAHSD17B10TSHRSOAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023028085-A2 ANTISENSE OLIGONUCLEOTIDE THERAPY FOR H3.3 K27M DIFFUSE MIDLINE GLIOMAS COLD SPRING HARBOR LABORATORY (US) 2023-03-02 WO disclosed
US-11535673-B2 Chimeric activators: quantitatively designed protein therapeutics and uses thereof President and Fellows of Harvard CoHege (US) 2022-12-27 US disclosed
US-20220347136-A1 COMPOSITIONS AND METHODS FOR TREATING ALZHEIMER'S DISEASE ELEANORE BENNETT CHARITABLE TRUST #2 2022-11-03 US disclosed
US-11352624-B2 Reducing nonsense-mediated MRNA decay COLD SPRING HARBOR LABORATORY (US) 2022-06-07 US disclosed
US-20220162324-A1 CHIMERIC ACTIVATORS: QUANTITATIVELY DESIGNED PROTEIN THERAPEUTICS AND USES THEREOF PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2022-05-26 US disclosed
EP-2140004-B1 GENETIC SUPPRESSION AND REPLACEMENT THE PROVOST FELLOWS FOUND SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIV T (IE) 2022-01-12 EP disclosed
US-20200291100-A1 TREATMENT OF AGE-RELATED AND MITOCHONDRIAL DISEASES BY INHIBITION OF HIF-1 ALPHA FUNCTION PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2020-09-17 US disclosed
US-20200283762-A1 REDUCING NONSENSE-MEDIATED MRNA DECAY COLD SPRING HARBOR LABORATORY (US) 2020-09-10 US disclosed
EP-3690048-A1 REDUCING NONSENSE-MEDIATED MRNA DECAY COLD SPRING HARBOR LABORATORY (US) 2020-08-05 EP disclosed
US-10647983-B2 Reducing nonsense-mediated mRNA decay COLD SPRING HARBOR LABORATORY (US) 2020-05-12 US disclosed
WO-2008150438-A1 PMEA LIPID CONJUGATES LUITPOLD PHARMACEUTICALS, INC. (US) 2008-12-11 WO disclosed
WO-2008130261-A1 TREATMENT OF INFECTIONS BY CARBON MONOXIDE ALFAMA - INVESTIGAÇAO E DESENVOLVIMENTO DE PRODUTOS FARMACEUTICOS LDA. (PT) 2008-10-30 WO disclosed
WO-2008125846-A2 GENETIC SUPPRESSION AND REPLACEMENT THE PROVOST, FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH (IE) 2008-10-23 WO disclosed
WO-2008124086-A2 CHIMERIC ACTIVATORS: QUANTITATIVELY DESIGNED PROTEIN THERAPEUTICS AND USES THEREOF PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2008-10-16 WO disclosed
WO-2008051523-A2 CARBAZOLE DERIVATIVES USEFUL AS MEDICAMENTS IN CANCER THERAPY GEORGETOWN UNIVERSITY (US) 2008-05-02 WO disclosed
US-20080090782-A1 Materials and methods to potentiate cancer treatment LUITPOLD PHARMACEUTICALS, INC. (US) 2008-04-17 US disclosed
US-7179912-B2 Materials and methods to potentiate cancer treatment ICOS CORPORATION (US) 2007-02-20 US disclosed
EP-1351946-A2 MATERIALS AND METHODS TO POTENTIATE CANCER TREATMENT ICOS CORPORATION (US) 2003-10-15 EP disclosed
US-20020165218-A1 Materials and methods to potentiate cancer treatment LUITPOLD PHARMACEUTICALS, INC. 2002-11-07 US disclosed
WO-2002020500-A2 MATERIALS AND METHODS TO POTENTIATE CANCER TREATMENT ICOS CORPORATION (US) 2002-03-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080090782-A1 Materials and methods to potentiate cancer treatment DCK, CHEK2, CHEK1 ALDH1A1 3519/4885LMNA 834/4885HSD17B10 4466/4885
US-20020165218-A1 Materials and methods to potentiate cancer treatment DCK, CHEK2, CHEK1 ALDH1A1 3519/4885LMNA 834/4885HSD17B10 4466/4885
US-20220347136-A1 COMPOSITIONS AND METHODS FOR TREATING ALZHEIMER'S DISEASE IAPP, PSEN1, IGF1R ALDH1A1 3278/4885LMNA 872/4885HSD17B10 4563/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.