Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 6/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14696690 | 1.00 | CYP3A4 (0.43) | CYP3A4TDP1ALDH1A1ALOX15ESR1 | |
| SCHEMBL289857 | 0.97 | CYP3A4 (0.45) | CYP3A4TDP1ALDH1A1ALOX15ESR1 | |
| SCHEMBL19093066 | 0.94 | CYP3A4 (0.43) | CYP3A4TDP1ALDH1A1ALOX15ESR1 | |
| SCHEMBL18796532 | 0.94 | CYP3A4 (0.43) | CYP3A4TDP1ALDH1A1ALOX15ESR1 | |
| Hydrochloric Acid SCHEMBL31467528 | 0.94 | CYP3A4 (0.43) | CYP3A4TDP1ALDH1A1ALOX15ESR1 | |
| Bromide SCHEMBL28700347 | 0.94 | CYP3A4 (0.43) | CYP3A4TDP1ALDH1A1ALOX15ESR1 | |
| Hydrochloric Acid SCHEMBL31568007 | 0.94 | CYP3A4 (0.43) | CYP3A4TDP1ALDH1A1ALOX15ESR1 | |
| Hydrochloric Acid SCHEMBL1603386 | 0.92 | CYP3A4 (0.41) | CYP3A4TDP1ALDH1A1ALOX15ESR1 | |
| Hydrochloric Acid SCHEMBL27810339 | 0.92 | CYP3A4 (0.41) | CYP3A4TDP1ALDH1A1ALOX15ESR1 | |
| SCHEMBL28001639 | 0.90 | CYP3A4 (0.39) | CYP3A4TDP1ALDH1A1ALOX15ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250340507-A1 | METHODS FOR SYNTHESIZING SUBSTITUTED TETRACYCLINE COMPOUNDS | PARATEK PHARM INNC (US) | 2025-11-06 | — | — | US | claimed |
| CN-106865526-B | β-graphite alkene and its synthetic method and application in energy storage field | 四川大学 | 2019-01-25 | — | — | CN | claimed |
| US-10118912-B2 | Process for the preparation of Ledipasvir | OPTIMUS DRUGS PRIVATE LTD. (IN) | 2018-11-06 | — | — | US | claimed |
| WO-2017072596-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF LEDIPASVIR | OPTIMUS DRUGS (P) LTD (IN) | 2017-05-04 | — | — | WO | claimed |
| US-20250340507-A1 | METHODS FOR SYNTHESIZING SUBSTITUTED TETRACYCLINE COMPOUNDS | PARATEK PHARM INNC (US) | 2025-11-06 | — | — | US | disclosed |
| CN-118026957-A | Three-component coupling method for aromatic trifluoroalkyl compound, conjugated olefin and nucleophilic reagent | 国科大杭州高等研究院 | 2024-05-14 | — | — | CN | disclosed |
| CN-117164580-A | Preparation method of KRAS G12C inhibitor and intermediate thereof | 苏州泽璟生物制药股份有限公司 | 2023-12-05 | — | — | CN | disclosed |
| CN-107001281-A | Substituted benzothiophene radical derivative is used as the GPR40 activators for treating type ii diabetes | 詹森药业有限公司 | 2017-08-01 | — | — | CN | disclosed |
| WO-2017072596-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF LEDIPASVIR | OPTIMUS DRUGS (P) LTD (IN) | 2017-05-04 | — | — | WO | disclosed |
| CN-102884063-B | Can be used as the azabicyclo imdazole derivatives of the replacement of TRPM8 receptor modulators | JANSSEN PHARMACEUTICA N.V. (BE) | 2015-11-25 | — | — | CN | disclosed |
| CN-101896461-A | Gamma secretase modulators | AMGEN INC | 2010-11-24 | — | — | CN | disclosed |
| EP-2176216-A1 | METHODS FOR SYNTHESIZING SUBSTITUTED TETRACYCLINE COMPOUNDS | Paratek Pharmaceuticals, Inc. (US) | 2010-04-21 | — | — | EP | disclosed |
| CN-100528845-C | Pyrazolyl arync | BAYER CHEMICAL PRODUCT AG (DE) | 2009-08-19 | — | — | CN | disclosed |
| WO-2009009042-A1 | METHODS FOR SYNTHESIZING SUBSTITUTED TETRACYCLINE COMPOUNDS | PARATEK PHARMACEUTICALS, INC. (US) | 2009-01-15 | — | — | WO | disclosed |
| CN-1517339-A | Pyrazolyl arync | 拜尔化学品股份公司 | 2004-08-04 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10118912-B2 | Process for the preparation of Ledipasvir | SAMHD1, POLI, PNP | CYP3A4 43/4885TDP1 727/4885ALDH1A1 1979/4885 |
| US-20250340507-A1 | METHODS FOR SYNTHESIZING SUBSTITUTED TETRACYCLINE COMPOUNDS | TET3, TET1, DHFR | CYP3A4 1280/4885TDP1 1297/4885ALDH1A1 4075/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.