Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 5/20 | 0.47 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.45 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.45 |
| ▸ | LAP3 | P28838 | 2/20 | 0.44 |
| ▸ | S1PR2 | O95136 | 7/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 7/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 7/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 6/20 | 0.39 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14742785 | 0.89 | BBOX1 (0.41) | FDPSLAP3BBOX1 | |
| SCHEMBL8010 | 0.89 | BBOX1 (0.41) | FDPSLAP3BBOX1 | |
| Phosphoric Acid SCHEMBL9095324 | 0.87 | BBOX1 (0.41) | FDPSBBOX1 | |
| Water SCHEMBL17373732 | 0.87 | BBOX1 (0.39) | FDPSLAP3BBOX1 | |
| Hydrochloric Acid SCHEMBL434365 | 0.87 | MAPT (0.43) | FDPSLAP3BBOX1 | |
| Bromide SCHEMBL8416789 | 0.87 | BBOX1 (0.39) | FDPSLAP3BBOX1 | |
| SCHEMBL23270963 | 0.86 | GGPS1 (0.39) | FDPSLPAR3LPAR2LAP3S1PR2 | |
| Hydrochloric Acid SCHEMBL2355625 | 0.85 | MAPT (0.41) | FDPSLAP3BBOX1 | |
| Hydrochloric Acid SCHEMBL933391 | 0.85 | MAPT (0.41) | FDPSLAP3BBOX1 | |
| Hydroxyamine SCHEMBL8584616 | 0.85 | BBOX1 (0.43) | LAP3BBOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9884899-B2 | Methods for treating fibrosis using CRP antagonists | PROMEDIOR, INC. (US) | 2018-02-06 | — | — | US | disclosed |
| EP-2176287-A2 | TREATMENT AND DIAGNOSTIC METHODS FOR FIBROSIS RELATED DISORDERS | Promedior, Inc. (US) | 2010-04-21 | — | — | EP | disclosed |
| US-20090202520-A1 | Treatment and diagnostic methods for fibrosis related disorders | PROMEDIOR, INC. (US) | 2009-08-13 | — | — | US | disclosed |
| WO-2009009019-A2 | TREATMENT AND DIAGNOSTIC METHODS FOR FIBROSIS RELATED DISORDERS | PROMEDIOR, INC. (US) | 2009-01-15 | — | — | WO | disclosed |