Hydrochloric Acid

Hydrochloric Acid

SCHEMBL933391

C[N+](C)(C)CC(O)P(=O)(O)O.[CaH2].[Cl-]

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CHRM2 known ✓ P08172 2/20 0.31
CHRM1 known ✓ P11229 2/20 0.31
CHRM3 known ✓ P20309 1/20 0.30
MAPT P10636 3/20 0.41
BBOX1 O75936 2/20 0.41
SLC22A16 Q86VW1 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.34
GALR3 O60755 1/20 0.34
BLM P54132 1/20 0.34
LMNA P02545 3/20 0.33
TSHR P16473 2/20 0.31
CHRM4 P08173 2/20 0.31
TBXA2R P21731 1/20 0.31
FDPS P14324 2/20 0.31
LAP3 P28838 1/20 0.31
CPT2 P23786 1/20 0.30
CPT1A P50416 1/20 0.30
CHRM5 P08912 1/20 0.30
CYP2C9 P11712 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL434365 0.98 MAPT (0.43) MAPTBBOX1SLC22A16SMN1; SMN2GALR3
Hydrochloric Acid SCHEMBL2355625 0.95 MAPT (0.41) MAPTBBOX1SLC22A16SMN1; SMN2GALR3
SCHEMBL8010 0.95 BBOX1 (0.41) MAPTBBOX1SLC22A16SMN1; SMN2GALR3
SCHEMBL14742785 0.95 BBOX1 (0.41) MAPTBBOX1SLC22A16SMN1; SMN2GALR3
Water SCHEMBL17373732 0.93 BBOX1 (0.39) MAPTBBOX1SLC22A16SMN1; SMN2GALR3
Bromide SCHEMBL8416789 0.93 BBOX1 (0.39) MAPTBBOX1SLC22A16SMN1; SMN2GALR3
Hydroxyamine SCHEMBL8584616 0.91 BBOX1 (0.43) MAPTBBOX1SLC22A16LMNATSHR
Phosphoric Acid SCHEMBL9095324 0.88 BBOX1 (0.41) MAPTBBOX1SLC22A16SMN1; SMN2TSHR
Glycerin SCHEMBL691939 0.85 SLC22A16 (0.42) MAPTBBOX1SLC22A16SMN1; SMN2LMNA
Hexane SCHEMBL3645235 0.85 FDPS (0.47) BBOX1FDPSLAP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116768948-A Method for synthesizing urine phosphorylcholine in citicoline injection 山东玉满坤生物科技有限公司 2023-09-19 CN claimed
US-6773822-B2 ANTIFUNGAL AGENT MAY BE PRESENT IN THE GYPSUM CORE AND/OR ON ONE OR BOTH OF THE PAPER FACINGS, AND MAY BE ENCAPSULATED IN A MATERIAL THAT RELEASES THE ANTIFUNGAL AGENT OVER TIME AND/OR UPON EXPOSURE TO MOISTURE. TEMPLE-INLAND FOREST PRODUCTS CORPORATION 2004-08-10 US claimed
EP-4393934-A1 METHOD FOR PRODUCING CYTIDINE-5'-DIPHOSPHATE COMPOUND Kyowa Hakko Bio Co., Ltd. (JP) 2024-07-03 EP disclosed
CN-113816991-B Preparation method of choline calcium chloride phosphate 拓新药业集团股份有限公司 2023-12-15 CN disclosed
US-20230365602-A1 COMPOUND FOR USE IN THE TREATMENT OF PROTOZOAL DISEASES AND PROCESS FOR PRODUCTION OF SAID COMPOUND QUADREL S.R.L. (IT) 2023-11-16 US disclosed
WO-2023211988-A2 COMPOSITIONS AND METHODS FOR ANTI-PHOSPHOCHOLINE ACTIVE IMMUNOTHERAPY DUKE UNIVERSITY (US) 2023-11-02 WO disclosed
CN-116768948-A Method for synthesizing urine phosphorylcholine in citicoline injection 山东玉满坤生物科技有限公司 2023-09-19 CN disclosed
EP-4216960-A1 COMPOUND FOR USE IN THE TREATMENT OF PROTOZOAL DISEASES AND PROCESS FOR PRODUCTION OF SAID COMPOUND Quadrel S.r.l. (IT) 2023-08-02 EP disclosed
EP-3999049-A1 METHODS USEFUL IN TREATING CANCERS HARBORING A KRAS OR HRAS MUTATION OR AMPLIFICATION Memorial Sloan Kettering Cancer Center (US) 2022-05-25 EP disclosed
EP-2905361-B1 METHOD OF FORMING A METAL COATING TOYOTA MOTOR CO LTD (JP) 2022-01-05 EP disclosed
CN-113816991-A Preparation method of choline calcium phosphochloride 新乡拓新药业股份有限公司 2021-12-21 CN disclosed
WO-2005049293-A2 CEMENTITIOUS SLAB PRODUCTS HAVING ANTIMICROBIAL PROPERTIES MICROBAN PRODUCTS COMPANY (US) 2005-06-02 WO disclosed
US-20050106336-A1 Cementitious slab products having antimicrobial properties MICROBAN PRODUCTS COMPANY (US) 2005-05-19 US disclosed
WO-2005014256-A1 COMPOSITE MATERIAL HAVING THE APPEARANCE OF NATURAL STONE COSENTINO, S.A. (ES) 2005-02-17 WO disclosed
US-6773822-B2 ANTIFUNGAL AGENT MAY BE PRESENT IN THE GYPSUM CORE AND/OR ON ONE OR BOTH OF THE PAPER FACINGS, AND MAY BE ENCAPSULATED IN A MATERIAL THAT RELEASES THE ANTIFUNGAL AGENT OVER TIME AND/OR UPON EXPOSURE TO MOISTURE. TEMPLE-INLAND FOREST PRODUCTS CORPORATION 2004-08-10 US disclosed
EP-1421242-A1 ANTIFUNGAL GYPSUM BOARD Temple-Inland Forest Products Corporation (US) 2004-05-26 EP disclosed
US-6680127-B2 COMPRISING AN ANTIFUNGAL AGENT AND A RETENTION AID, SUCH AS A SURFACTANT, IN ONE OR MORE PAPER FACINGS. TEMPLE-INLAND FOREST PRODUCTS, CORPORATION 2004-01-20 US disclosed
US-20030035981-A1 Antifungal gypsum board TIN INC. D/B/A TEMPLE-INLAND 2003-02-20 US disclosed
WO-2003012218-A1 ANTIFUNGAL GYPSUM BOARD TEMPLE-INLAND FOREST PRODUCTS CORPORATION (US) 2003-02-13 WO disclosed
US-20030031898-A1 Antifungal gypsum board TIN INC. D/B/A TEMPLE-INLAND 2003-02-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230365602-A1 COMPOUND FOR USE IN THE TREATMENT OF PROTOZOAL DISEASES AND PROCESS FOR PRODUCTION OF SAID COMPOUND PIGO, PIGS, AGPS CHRM2 4302/4885CHRM1 4491/4885CHRM3 4406/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.