Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAP3K7 | O43318 | 3/20 | 0.33 |
| ▸ | TAB1 | Q15750 | 3/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.30 |
| ▸ | ICMT | O60725 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21366340 | 0.81 | KDM4E (0.42) | GAAALDH1A1HSD17B10 | |
| SCHEMBL21366517 | 0.80 | HDAC4 (0.33) | ALDH1A1 | |
| SCHEMBL7676177 | 0.77 | HTT (0.44) | HTTSIRT1GAANPSR1ALDH1A1 | |
| SCHEMBL11306610 | 0.76 | CCR1 (0.31) | — | |
| SCHEMBL13877864 | 0.74 | LMNA (0.36) | MAP3K7TAB1ALDH1A1L3MBTL1 | |
| SCHEMBL2756555 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL4540561 | 0.73 | HTT (0.36) | HTTGAANPSR1HSD17B10 | |
| SCHEMBL3643388 | 0.69 | HTT (0.34) | HTTMAP3K7TAB1 | |
| SCHEMBL20595245 | 0.67 | HCAR2 (0.36) | ALDH1A1L3MBTL1 | |
| SCHEMBL15471417 | 0.67 | ALDH1A1 (0.31) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2167474-A1 | UROCANIC ACID DERIVATIVES USEFUL FOR THE TREATMENT OF IMMUNE-RELATED AND INFLAMMATORY DISEASES | Valletta Health IP EE B.V. (NL) | 2010-03-31 | — | — | EP | disclosed |
| WO-2008153385-A1 | UROCANIC ACID DERIVATIVES USEFUL FOR THE TREATMENT OF IMMUNE-RELATED AND INFLAMMATORY DISEASES | VALLETTA HEALTH B.V. (NL) | 2008-12-18 | — | — | WO | disclosed |