Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.39 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.39 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.39 |
| ▸ | YARS1 | P54577 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3639104 | 1.00 | LCK (0.44) | LCKOPRK1ERAP2LNPEPERAP1 | |
| SCHEMBL12083525 | 0.94 | LCK (0.49) | LCKOPRK1ERAP2LNPEPERAP1 | |
| SCHEMBL3733282 | 0.87 | LCK (0.53) | LCKOPRK1ERAP2LNPEPERAP1 | |
| SCHEMBL3801519 | 0.87 | LCK (0.53) | LCKOPRK1ERAP2LNPEPERAP1 | |
| SCHEMBL8093509 | 0.87 | LCK (0.53) | LCKOPRK1ERAP2LNPEPERAP1 | |
| Hydrochloric Acid SCHEMBL3729333 | 0.86 | LCK (0.52) | LCKOPRK1ERAP2LNPEPERAP1 | |
| Hydrochloric Acid SCHEMBL3640073 | 0.86 | LCK (0.52) | LCKOPRK1ERAP2LNPEPERAP1 | |
| Hydrochloric Acid SCHEMBL3746967 | 0.86 | LCK (0.52) | LCKOPRK1ERAP2LNPEPERAP1 | |
| SCHEMBL1069987 | 0.83 | OPRK1 (0.49) | LCKOPRK1ERAP2LNPEPERAP1 | |
| SCHEMBL22290230 | 0.83 | OPRK1 (0.49) | LCKOPRK1ERAP2LNPEPERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2176217-A1 | AMINO ACID DERIVATIVES | Proximagen Ltd. (GB) | 2010-04-21 | — | — | EP | disclosed |
| WO-2009007696-A1 | AMINO ACID DERIVATIVES | PROXIMAGEN LTD. (GB) | 2009-01-15 | — | — | WO | disclosed |