Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 2/20 | 0.49 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.41 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | YARS1 | P54577 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3645537 | 0.94 | LCK (0.44) | LCKLNPEPERAP2ERAP1OPRK1 | |
| Trifluoroacetic Acid SCHEMBL3639104 | 0.94 | LCK (0.44) | LCKLNPEPERAP2ERAP1OPRK1 | |
| SCHEMBL3801519 | 0.92 | LCK (0.53) | LCKLNPEPERAP2ERAP1OPRK1 | |
| SCHEMBL3733282 | 0.92 | LCK (0.53) | LCKLNPEPERAP2ERAP1OPRK1 | |
| SCHEMBL8093509 | 0.92 | LCK (0.53) | LCKLNPEPERAP2ERAP1OPRK1 | |
| Hydrochloric Acid SCHEMBL3729333 | 0.91 | LCK (0.52) | LCKLNPEPERAP2ERAP1OPRK1 | |
| Hydrochloric Acid SCHEMBL3746967 | 0.91 | LCK (0.52) | LCKLNPEPERAP2ERAP1OPRK1 | |
| Hydrochloric Acid SCHEMBL3640073 | 0.91 | LCK (0.52) | LCKLNPEPERAP2ERAP1OPRK1 | |
| SCHEMBL22290230 | 0.88 | OPRK1 (0.49) | LCKLNPEPERAP2ERAP1OPRK1 | |
| SCHEMBL1069987 | 0.88 | OPRK1 (0.49) | LCKLNPEPERAP2ERAP1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8258097-B2 | Amino acid derivatives | PROXIMAGEN LTD. (GB) | 2012-09-04 | — | — | US | disclosed |
| US-20100190725-A1 | AMINO ACID DERIVATIVES | PROXIMAGEN LTD. (GB) | 2010-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190725-A1 | AMINO ACID DERIVATIVES | NPR3, NPY4R, GFRA3 | LCK 3696/4885LNPEP 737/4885ERAP2 2866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.