SCHEMBL3645580

SCHEMBL3645580

OC(OCC1CO1)C1CO1

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.38
ALDH1A1 P00352 6/20 0.37
MAPK1 P28482 1/20 0.34
TP53 P04637 2/20 0.34
CYP3A4 P08684 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
TDP1 Q9NUW8 2/20 0.32
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25210172 0.78 TSHR (0.42) TSHRALDH1A1MAPK1TP53CYP3A4
SCHEMBL24938789 0.77 TP53 (0.43) TSHRALDH1A1MAPK1TP53CYP3A4
SCHEMBL21670993 0.77 TP53 (0.43) TSHRALDH1A1MAPK1TP53CYP3A4
SCHEMBL10948286 0.75
SCHEMBL11196650 0.74
SCHEMBL1261540 0.74
SCHEMBL25236886 0.74 TSHR (0.39) TSHRALDH1A1MAPK1TP53CYP3A4
SCHEMBL19155242 0.74
SCHEMBL8950934 0.73 TSHR (0.38) TSHRALDH1A1MAPK1TP53CYP3A4
SCHEMBL4744554 0.73 TSHR (0.38) TSHRALDH1A1MAPK1TP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 239 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106633168-A Preparation method of monodisperse and large-particle-diameter polymer microspheres 扬州倍赛德生物科技有限公司 2017-05-10 CN claimed
CN-106590371-A Low-VOC matte alkyd resin and synthesis method thereof 帝斯曼先达合成树脂(佛山)有限公司 2017-04-26 CN claimed
CN-106523511-A Preparation method of high-rigidity composite material transmission shaft 江苏欧亚铂瑞碳复合材料有限公司 2017-03-22 CN claimed
CN-106496543-A A kind of preparation method of allyl alcohol polyether glycidyl ether 浙江润禾有机硅新材料有限公司 2017-03-15 CN claimed
CN-104864267-B A kind of combustible ice formation inhibitor and preparation method thereof and purposes 东北石油大学 2017-03-08 CN claimed
CN-106479417-A LED packaging plastic and preparation method thereof 深圳市宝力新材料有限公司 2017-03-08 CN claimed
CN-104403109-B Preparation method for reactive polyamidoamine dendrime rubber antioxidant 华南理工大学 2017-02-22 CN claimed
CN-104911900-B Method for preparing CNT (carbon nano tube)/CF (carbon fiber) multi-scale reinforcement in large scale 哈尔滨工业大学 2017-02-01 CN claimed
CN-106367009-A Bonding adhesive 无锡万能胶粘剂有限公司 2017-02-01 CN claimed
CN-104774527-B Preparation method of epoxy glass flake coating for oceanic tidal range/splash zone 厦门双瑞船舶涂料有限公司 2017-01-25 CN claimed
CN-105799285-A Thermoplastic composite laminate and products made therefrom 杜邦公司 2016-07-27 CN claimed
CN-105713174-A Hyperbranched resin pigment dispersant, preparation method and color paste thereof, and applications of color paste 立邦投资有限公司 2016-06-29 CN claimed
CN-105621929-A Cold-recycling emulsifier for surface layer of asphalt pavement and preparation method thereof SHANXI PROVINCIAL RES INST COMMUNICATIONS 2016-06-01 CN claimed
CN-104105475-A Hair composition with improved rheology UNILEVER NV 2014-10-15 CN claimed
EP-2181166-A2 UNDERLAYER COATING COMPOSITION BASED ON A CROSSLINKABLE POLYMER AZ Electronic Materials USA Corp. (US) 2010-05-05 EP claimed
WO-2009019575-A2 UNDERLAYER COATING COMPOSITION BASED ON A CROSSLINKABLE POLYMER AZ ELECTRONIC MATERIALS USA CORP. (DE) 2009-02-12 WO claimed
US-20090035704-A1 Underlayer Coating Composition Based on a Crosslinkable Polymer AZ ELECTRONIC MATERIALS USA CORP. 2009-02-05 US claimed
CN-101060827-A Dental compositions comprising epoxy-functional carbosilane compounds 3M ESPE AG (DE) 2007-10-24 CN claimed
CN-101018536-A Dental composition containing epoxy functional polymerizable compounds 3M ESPE AG (DE) 2007-08-15 CN claimed
US-4070348-A CROSSLINKING ROHM GMBH (DT) 1978-01-24 US claimed