Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31425200 | 0.74 | — | — | |
| SCHEMBL11418992 | 0.74 | TSHR (0.39) | TSHRALDH1A1TDP1MAPK1SMN1; SMN2 | |
| SCHEMBL7193893 | 0.74 | — | — | |
| SCHEMBL30179645 | 0.73 | TSHR (0.39) | TSHRALDH1A1TDP1MAPK1SMN1; SMN2 | |
| SCHEMBL4744554 | 0.73 | TSHR (0.38) | TSHRALDH1A1TDP1MAPK1SMN1; SMN2 | |
| SCHEMBL3645580 | 0.73 | TSHR (0.38) | TSHRALDH1A1TDP1MAPK1SMN1; SMN2 | |
| SCHEMBL6051764 | 0.73 | ALDH1A1 (0.41) | TSHRALDH1A1TDP1MAPK1SMN1; SMN2 | |
| SCHEMBL5400750 | 0.73 | TSHR (0.38) | TSHRALDH1A1TDP1MAPK1SMN1; SMN2 | |
| SCHEMBL9515799 | 0.73 | TSHR (0.38) | TSHRALDH1A1TDP1MAPK1SMN1; SMN2 | |
| SCHEMBL2390211 | 0.73 | TSHR (0.38) | TSHRALDH1A1TDP1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5567748-A | A REACTION PRODUCT OF HYDROPHILIC POLYOXYALKYLENE AMINES AND DIGLYCIDYL ETHERS OF A POLYALKYLENE GLYCOL; CURING AGENTS, EMULSIFIERS, DISPERSANTS; WATERBASE PAINTS | THE DOW CHEMICAL COMPANY (US) | 1996-10-22 | — | — | US | disclosed |
| EP-0617726-B1 | WATER COMPATIBLE AMINE TERMINATED RESIN USEFUL FOR CURING EPOXY RESINS | DOW CHEMICAL CO (US) | 1996-01-31 | — | — | EP | disclosed |
| EP-0617726-A1 | WATER COMPATIBLE AMINE TERMINATED RESIN USEFUL FOR CURING EPOXY RESINS. | DOW CHEMICAL CO (US) | 1994-10-05 | — | — | EP | disclosed |
| WO-1993012187-A1 | WATER COMPATIBLE AMINE TERMINATED RESIN USEFUL FOR CURING EPOXY RESINS | THE DOW CHEMICAL COMPANY (US) | 1993-06-24 | — | — | WO | disclosed |