Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5752165 | 0.80 | — | — | |
| SCHEMBL5165263 | 0.59 | ALDH1A1 (0.44) | ALDH1A1POLBRXFP1MEN1BLM | |
| SCHEMBL13735762 | 0.59 | ALDH1A1 (0.65) | ALDH1A1POLBRXFP1PARP1MEN1 | |
| SCHEMBL3670371 | 0.58 | ALDH1A1 (0.32) | ALDH1A1POLBRXFP1 | |
| SCHEMBL13735766 | 0.57 | ALDH1A1 (0.63) | ALDH1A1POLBRXFP1PARP1MEN1 | |
| SCHEMBL11279379 | 0.56 | MEN1 (0.34) | ALDH1A1POLBRXFP1MEN1BLM | |
| SCHEMBL2775270 | 0.55 | ALDH1A1 (0.44) | ALDH1A1POLBRXFP1MEN1BLM | |
| SCHEMBL5742205 | 0.53 | ALDH1A1 (0.52) | ALDH1A1POLBRXFP1PARP1MEN1 | |
| SCHEMBL5752168 | 0.53 | — | — | |
| SCHEMBL5793769 | 0.53 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2178877-A1 | ANTI-VIRAL COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | GlaxoSmithKline LLC (US) | 2010-04-28 | — | — | EP | disclosed |
| WO-2009011787-A1 | ANTI-VIRAL COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | GENELABS TECHNOLOGIES, INC. (US) | 2009-01-22 | — | — | WO | disclosed |