Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 11/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 9/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29032247 | 0.77 | SLC6A4 (0.42) | SLC6A4ATMHTR1A | |
| SCHEMBL7439150 | 0.73 | SLC6A4 (0.39) | SLC6A4ATMGBA1PTGS1PTGS2 | |
| SCHEMBL31063566 | 0.73 | SLC6A4 (0.58) | SLC6A4HTR1A | |
| SCHEMBL26586493 | 0.71 | — | — | |
| SCHEMBL18838079 | 0.71 | TRPA1 (0.41) | — | |
| SCHEMBL4776308 | 0.71 | TSHR (0.31) | — | |
| SCHEMBL1119559 | 0.70 | GBA1 (0.43) | GBA1 | |
| SCHEMBL1119520 | 0.70 | SLC6A2 (0.46) | SLC6A4ATMGBA1 | |
| SCHEMBL31063429 | 0.69 | HTT (0.50) | SLC6A4HTR1A | |
| Ammonia Solution, Strong SCHEMBL987776 | 0.69 | SLC6A2 (0.45) | SLC6A4ATMGBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2170850-A1 | NOVEL DICARBOXYLIC ACID DERIVATIVES AS S1P1 RECEPTOR AGONISTS | BIOPROJET (FR) | 2010-04-07 | — | — | EP | disclosed |
| WO-2008152149-A1 | NOVEL DICARBOXYLIC ACID DERIVATIVES AS S1P1 RECEPTOR AGONISTS | BIOPROJET (FR) | 2008-12-18 | — | — | WO | disclosed |