Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | TTR | P02766 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11019831 | 0.78 | PTPRC (0.34) | TSHRCA1CA2TTR | |
| SCHEMBL18838079 | 0.77 | TRPA1 (0.41) | CA2 | |
| SCHEMBL1535743 | 0.74 | IDO1 (0.38) | TSHRTTR | |
| SCHEMBL17186390 | 0.74 | TAAR1 (0.50) | — | |
| SCHEMBL2496840 | 0.73 | ALDH1A1 (0.37) | TTR | |
| SCHEMBL31511762 | 0.73 | TTR (0.43) | CA1CA2TTR | |
| SCHEMBL7379965 | 0.73 | S1PR1 (0.45) | TSHRCA1CA2TTR | |
| SCHEMBL30831865 | 0.73 | ALDH1A1 (0.37) | TTR | |
| SCHEMBL15912481 | 0.73 | KDM1A (0.37) | TSHRCA1CA2TTR | |
| SCHEMBL3645800 | 0.71 | SLC6A4 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1984369-A2 | NITROIMIDAZOLE COMPOUNDS | Novartis AG (CH) | 2008-10-29 | — | — | EP | disclosed |
| WO-2007075872-A2 | NITROIMIDAZOLE COMPOUNDS | NOVARTIS AG (CH) | 2007-07-05 | — | — | WO | disclosed |