Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CASP2 | P42575 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3648005 | 1.00 | MEN1 (0.34) | MEN1MAPTKMT2AMAPK1CASP2 | |
| Hydrochloric Acid SCHEMBL3648019 | 1.00 | MEN1 (0.34) | MEN1MAPTKMT2AMAPK1CASP2 | |
| Hydrochloric Acid SCHEMBL3647822 | 1.00 | MEN1 (0.34) | MEN1MAPTKMT2AMAPK1CASP2 | |
| SCHEMBL1858365 | 0.99 | MEN1 (0.34) | MEN1MAPTKMT2AAPAF1MITF | |
| SCHEMBL1735956 | 0.99 | MEN1 (0.34) | MEN1MAPTKMT2AAPAF1MITF | |
| SCHEMBL1736109 | 0.99 | MEN1 (0.34) | MEN1MAPTKMT2AAPAF1MITF | |
| SCHEMBL1736114 | 0.99 | MEN1 (0.34) | MEN1MAPTKMT2AAPAF1MITF | |
| SCHEMBL1735066 | 0.99 | MEN1 (0.34) | MEN1MAPTKMT2AAPAF1MITF | |
| SCHEMBL358007 | 0.99 | MEN1 (0.34) | MEN1MAPTKMT2AAPAF1MITF | |
| SCHEMBL357139 | 0.94 | ALDH1A1 (0.34) | MEN1MAPTKMT2ASMN1; SMN2APAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2205545-A2 | PROCESSES FOR MAKING DIBUTYL ETHERS FROM 2-BUTANOL | E. I. du Pont de Nemours and Company (US) | 2010-07-14 | — | — | EP | disclosed |
| EP-2185495-A2 | PROCESSES FOR MAKING DIALKYL ETHERS FROM ALCOHOLS | E. I. du Pont de Nemours and Company (US) | 2010-05-19 | — | — | EP | disclosed |
| EP-2185494-A2 | PROCESSES FOR MAKING DIBUTYL ETHERS FROM ISOBUTANOL | E. I. du Pont de Nemours and Company (US) | 2010-05-19 | — | — | EP | disclosed |
| WO-2009032959-A2 | PROCESSES FOR MAKING DIALKYL ETHERS FROM ALCOHOLS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-03-12 | — | — | WO | disclosed |
| WO-2009032961-A2 | PROCESSES FOR MAKING DIBUTYL ETHERS FROM 2-BUTANOL | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-03-12 | — | — | WO | disclosed |
| WO-2009032962-A2 | PROCESSES FOR MAKING DIBUTYL ETHERS FROM ISOBUTANOL | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-03-12 | — | — | WO | disclosed |
| EP-2027225-A2 | VAPOR COMPRESSION UTILIZING IONIC LIQUID AS COMPRESSOR LUBRICANT | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-02-25 | — | — | EP | disclosed |
| EP-1882132-A2 | HYBRID VAPOR COMPRESSION-ABSORPTION CYCLE | E.I. du Pont de Nemours & Company (US) | 2008-01-30 | — | — | EP | disclosed |
| WO-2006124776-A9 | HYBRID VAPOR COMPRESSION-ABSORPTION CYCLE | DU PONT (US) | 2008-01-24 | — | — | WO | disclosed |
| WO-2007143051-A2 | VAPOR COMPRESSION UTILIZING IONIC LIQUID AS COMPRESSOR LUBRICANT | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-12-13 | — | — | WO | disclosed |
| WO-2006124776-A2 | HYBRID VAPOR COMPRESSION-ABSORPTION CYCLE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2006-11-23 | — | — | WO | disclosed |