Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4414189 | 0.94 | MAPT (0.55) | RAB9AMAPTALDH1A1KMT2ATSHR | |
| SCHEMBL1018873 | 0.92 | CA1 (0.47) | RAB9AALDH1A1TSHRNPC1SMN1; SMN2 | |
| SCHEMBL7611290 | 0.80 | MAPT (0.53) | RAB9AMAPTALDH1A1KMT2ATSHR | |
| SCHEMBL27555709 | 0.79 | TSHR (0.70) | RAB9AMAPTALDH1A1KMT2ATSHR | |
| Terephthalic Acid SCHEMBL4349174 | 0.79 | TSHR (0.70) | RAB9AMAPTALDH1A1KMT2ATSHR | |
| Terephthalic Acid SCHEMBL18394717 | 0.79 | TSHR (0.70) | RAB9AMAPTALDH1A1KMT2ATSHR | |
| SCHEMBL63466 | 0.79 | TSHR (0.70) | RAB9AMAPTALDH1A1KMT2ATSHR | |
| Terephthalic Acid SCHEMBL8811649 | 0.79 | TSHR (0.70) | RAB9AMAPTALDH1A1KMT2ATSHR | |
| SCHEMBL10366613 | 0.79 | ALDH1A1 (0.52) | RAB9AMAPTALDH1A1KMT2ATSHR | |
| SCHEMBL6617469 | 0.79 | MAPT (0.51) | RAB9AMAPTALDH1A1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2188257-A2 | SULFOXIMINE DERIVATIVES AS FACTOR XA INHIBITORS | Cadila Healthcare Limited (IN) | 2010-05-26 | — | — | EP | disclosed |
| WO-2009053999-A2 | SULFOXIMINE DERIVATIVES AS FACTOR XA INHIBITORS | CADILA HEALTHCARE LIMITED (IN) | 2009-04-30 | — | — | WO | disclosed |