Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITPR3 | Q14573 | 8/20 | 0.63 |
| ▸ | ITPR1 | Q14643 | 4/20 | 0.57 |
| ▸ | ITPR2 | Q14571 | 3/20 | 0.57 |
| ▸ | INPP5A | Q14642 | 2/20 | 0.55 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.55 |
| ▸ | AKT1 | P31749 | 1/20 | 0.55 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3654572 | 0.89 | ITPR3 (0.59) | ITPR3ITPR1ITPR2INPP5AINPPL1 | |
| SCHEMBL3075922 | 0.88 | PDPK1 (0.50) | ITPR3ITPR1ITPR2INPP5AINPPL1 | |
| SCHEMBL3073490 | 0.88 | PDPK1 (0.50) | ITPR3ITPR1ITPR2INPP5AINPPL1 | |
| SCHEMBL3075480 | 0.86 | GBA1 (0.66) | ITPR3ITPR1ITPR2INPP5AINPPL1 | |
| SCHEMBL8500705 | 0.86 | ITPR3 (0.57) | ITPR3ITPR1ITPR2INPP5AINPPL1 | |
| SCHEMBL8496576 | 0.86 | ITPR3 (0.57) | ITPR3ITPR1ITPR2INPP5AINPPL1 | |
| SCHEMBL9439428 | 0.79 | ITPR3 (1.00) | ITPR3ITPR1ITPR2INPP5AINPPL1 | |
| SCHEMBL356762 | 0.79 | ITPR3 (1.00) | ITPR3ITPR1ITPR2INPP5AINPPL1 | |
| SCHEMBL9439604 | 0.79 | ITPR3 (1.00) | ITPR3ITPR1ITPR2INPP5AINPPL1 | |
| SCHEMBL544343 | 0.79 | ITPR3 (1.00) | ITPR3ITPR1ITPR2INPP5AINPPL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2187892-A1 | METHOD AND MEANS FOR THE TREATMENT OF CACHEXIA | Bioneris AB (SE) | 2010-05-26 | — | — | EP | disclosed |
| WO-2009038533-A1 | METHOD AND MEANS FOR THE TREATMENT OF CACHEXIA | BIONERIS AB (SE) | 2009-03-26 | — | — | WO | disclosed |