Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | EDNRB | P24530 | 6/20 | 0.34 |
| ▸ | EDNRA | P25101 | 6/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.34 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL363298 | 0.90 | EGFR (0.32) | GAAMAPTTSHREDNRBEDNRA | |
| SCHEMBL440368 | 0.82 | KIF11 (0.41) | TSHRKMT2AKIF11CYP2C19CYP1A2 | |
| SCHEMBL362227 | 0.80 | EDNRB (0.33) | GAAMAPTEDNRBEDNRANR1I2 | |
| SCHEMBL363076 | 0.71 | EDNRB (0.30) | EDNRBEDNRA | |
| SCHEMBL10144369 | 0.70 | CYP1A2 (0.42) | GAAMAPTTSHREDNRBEDNRA | |
| SCHEMBL363777 | 0.68 | KMT2A (0.39) | MAPTTSHRPOLBKMT2AKIF11 | |
| SCHEMBL369625 | 0.67 | EDNRB (0.34) | GAAMAPTTSHREDNRBEDNRA | |
| SCHEMBL9340359 | 0.66 | CYP2C19 (0.42) | MAPTTSHRKMT2ACYP3A4CYP2D6 | |
| SCHEMBL6991557 | 0.66 | CYP2C9 (0.44) | TSHRKMT2ACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL1125158 | 0.66 | TAAR1 (0.52) | MAPTTSHRKMT2ACYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |